Protein amnionless Antibodies

AND AMN ELISA kits, Protein amnionless Proteins

Many biological assays use antibodies to detect Protein amnionless, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein amnionless in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein amnionless antibodies...

We validate the specificity of these antibodies to Protein amnionless by testing them on tissues known to express AMN positively and negatively. Browse below to find the AMN antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AMN Infographic by Boster Bio

All AMN Products

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Applications

Price

Anti-AMNLS Antibody

1 Citations

Human, Mouse

ELISA, WB

$380
Cat # A02337
100ul

Human Amnionless Recombinant Protein

SDS-PAGE

$287
Cat # PROTQ9BXJ7
Starting from 10ug

AMN Overview

Facts about Protein amnionless.

AMN 3D structure. Source: alphafold

Protein amnionless (AMN)

Necessary for efficient absorption of vitamin B12 (PubMed:12590260, PubMed:14576052). Required for normal CUBN- mediated protein transport in the kidney.

May direct the creation of back mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity). .

Gene Information

Human
Gene Name:	AMN
Uniprot:	Q9BXJ7
Entrez:	81693

Family

Belongs to:

No superfamily

Alternative Names

Protein amnionless

Molecular Weight

Mass (kDA):
47.754 kDA

Genomic Context


Human

Location:	14q32.32
Sequence:	14; NC_000014.9 (102922430..102933597)

Tissue Specificity

Long isoforms are highly expressed in small intestine, colon and kidney (renal proximal tubule epithelial cells). Shorter isoforms are detected at lower levels in testis, thymus and peripheral blood leukocytes.

Subcellular Localizations

[Isoform 1]: Apical cell membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Endosome membrane. Membrane, coated pit.; [Soluble protein amnionless]: Secreted.

Diseases

Recessive hereditary megaloblastic anemia 1 (RH-MGA1)

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AMN

References

PMID: 11279523 by Kalantry S., et al. The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain.

PMID: 12590260 by Tanner S.M., et al. Amnionless, essential for mouse gastrulation, is mutated in recessive hereditary megaloblastic anemia.