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- Table of Contents
Facts about Anaphase-promoting complex subunit 11.
May recruit the E2 ubiquitin-conjugating enzymes into the complex. .
Human | |
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Gene Name: | ANAPC11 |
Uniprot: | Q9NYG5 |
Entrez: | 51529 |
Belongs to: |
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RING-box family |
anaphase promoting complex subunit 11 (yeast APC11 homolog); anaphase promoting complex subunit 11; anaphase-promoting complex subunit 11; APC11 anaphase promoting complex subunit 11 homolog; APC11Hepatocellular carcinoma-associated RING finger protein; Apc11p; Cyclosome subunit 11; HSPC214; MGC882
Mass (kDA):
9.841 kDA
Human | |
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Location: | 17q25.3 |
Sequence: | 17; NC_000017.11 (81890790..81900533) |
Expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte.
Cytoplasm. Nucleus.
PMID: 11573242 by Chan A.H., et al. Molecular cloning and characterization of a RING-H2 finger protein, ANAPC11, the human homolog of yeast Apc11p.
PMID: 10922056 by Gmachl M., et al. The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex.