Anti-APC11 ANAPC11 Antibody

Apc11 antibody

Boster Bio Anti-APC11 ANAPC11 Antibody (Catalog # A08555-1). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A08555-1
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, WB

Product Name

Anti-APC11 ANAPC11 Antibody

View all Apc11 Antibodies

SKU/Catalog Number

A08555-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-APC11 ANAPC11 Antibody (Catalog # A08555-1). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

APC11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-APC11 ANAPC11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08555-1)

Host

Rabbit

Contents

APC11 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

APC11 antibody was raised against an 18 amino acid synthetic peptide near the center of human APC11. The immunogen is located within amino acids 70 - 120 of APC11.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

ULK4 antibody is human and mouse reactive. Multiple isoforms of ULK4 are known to exist.

Reactive Species

A08555-1 is reactive to ANAPC11 in Human, Mouse, Rat

Applications

A08555-1 is guaranteed for ELISA, IF, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

9.841kDa

Background of Apc11

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC11 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC11, together with APC2 and Ubc4, form the minimal APC ubiquitin ligase module.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

APC11 antibody can be used for detection of APC11 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For ANAPC11 (Source: Uniprot.org, NCBI)

Gene Name

ANAPC11

Full Name

Anaphase-promoting complex subunit 11

Weight

9.841kDa

Superfamily

RING-box family

Alternative Names

anaphase promoting complex subunit 11 (yeast APC11 homolog); anaphase promoting complex subunit 11; anaphase-promoting complex subunit 11; APC11 anaphase promoting complex subunit 11 homolog; APC11Hepatocellular carcinoma-associated RING finger protein; Apc11p; Cyclosome subunit 11; HSPC214; MGC882 ANAPC11 APC11, Apc11p, HSPC214 anaphase promoting complex subunit 11 anaphase-promoting complex subunit 11|APC11 anaphase promoting complex subunit 11 homolog|anaphase promoting complex subunit 11 (yeast APC11 homolog)|cyclosome subunit 11|hepatocellular carcinoma-associated RING finger protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ANAPC11, check out the ANAPC11 Infographic

ANAPC11 infographic

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In this infographic, you will see the following information for ANAPC11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A08555-1-0.1 mg

0.1 mg

$449

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