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- Table of Contents
AOC1 Antibodies
AND AOC1 ELISA kits, AOC1 Proteins
Many biological assays use antibodies to detect AOC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AOC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AOC1 antibodies...
Designing a Western blot for AOC1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AOC1 Western Blot GuideDesigning an IHC experiment for AOC1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the AOC1 IHC GuideAOC1 Infographic by Boster Bio
All AOC1 Products
Product
Figures
Specificity
Applications
Price
Anti-ABP1/AOC1 Antibody Picoband®
1 Citations
Human, Monkey
IF, IHC, ICC, WB
$370
Cat # PB10040
100 μg/vial
Cat # PB10040
100 μg/vial
Human, Monkey
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A08386-1
100 μg/vial
Cat # A08386-1
100 μg/vial
AOC1 Overview
Facts about Amiloride-sensitive amine oxidase [copper-containing].
Amiloride-sensitive amine oxidase [copper-containing] (AOC1)
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic reactions and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | AOC1 |
| Uniprot: | P19801 |
| Entrez: | 26 |
Family
| Belongs to: |
|---|
| copper/topaquinone oxidase family |
Alternative Names
ABP; ABP1; amiloride binding protein 1 (amine oxidase (copper-containing)); Amiloride-binding protein; amiloride-sensitive amine oxidase [copper-containing]; amiloride-sensitive amine oxidase; AOC1; AOC1DAOamiloride-binding protein-1; DAO1; Diamine Oxidase; EC 1.4.3; EC 1.4.3.22; Histaminase; KAO; Kidney amine oxidase
Molecular Weight
Mass (kDA):
85.378 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q36.1 |
| Sequence: | 7; NC_000007.14 (150824875..150861504) |
Tissue Specificity
Placenta and kidney.
Subcellular Localizations
Secreted, extracellular space.
Diseases
- Edema
- Fibrosis
- Cystic Fibrosis
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Dysequilibrium Syndrome
- Allergic Asthma
- Inflammation
- Retinopathy Of Prematurity
- Asthma
- Allergy
Pathways
- Endocytosis
- Localization
- Transport
- Cell Division
- Cell Cycle
- Receptor-mediated Endocytosis
- Actin Nucleation
- Clathrin-mediated Endocytosis
- Auxin Transport
- Cell Growth
- Chromosome Segregation
- Secretion
- Glycosylation
PTMs
- Phosphorylation
- Ubiquitination
- Cleavage
- Glycosylation
- Methylation
- Carboxylation
- Deamination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AOC1
bosterbio.com/bosterbio-gene-info-cards/AOC1
References
PMID: 2217167 by Barbry P., et al. Human kidney amiloride-binding protein: cDNA structure and functional expression.
PMID: 8182053 by Chassande O., et al. The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter.