AOC1 Antibodies

AND AOC1 ELISA kits, AOC1 Proteins

Many biological assays use antibodies to detect AOC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AOC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AOC1 antibodies...

We validate the specificity of these antibodies to AOC1 by testing them on tissues known to express AOC1 positively and negatively. Browse below to find the AOC1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AOC1 Infographic by Boster Bio

All AOC1 Products

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Anti-ABP1/AOC1 Antibody Picoband®

1 Citations 3 Q&As

Western blot analysis of ABP1/AOC1 using anti-ABP1/AOC1 antibody (PB10040)

IHC analysis of ABP1/AOC1 using anti-ABP1/AOC1 antibody (PB10040)

Human, Monkey

IF, IHC, ICC, WB

$370
Cat # PB10040
100 μg/vial

Anti-KAO AOC1 Antibody

Western blot analysis of extracts of various cell lines, using AOC1 antibody at 1:1000 dilution

Immunofluorescence analysis of HeLa cells using AOC1 Polyclonal Antibody at dilution of 1:100

Immunofluorescence analysis of NIH-3T3 cells using AOC1 Polyclonal Antibody at dilution of 1:100

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A08386
100ul

ABP1 (AOC1) (NM_001091) Human Recombinant Protein

Coomassie blue staining of purified AOC1 protein

$1249
Cat # PROTP19801
20 µg

Anti-ABP1/AOC1 Antibody Picoband®

Western blot analysis of ABP1/AOC1 using anti-ABP1/AOC1 antibody (A08386-1)

IHC analysis of ABP1/AOC1 using anti-ABP1/AOC1 antibody (A08386-1)

IF analysis of ABP1/AOC1 using anti-ABP1/AOC1 antibody (A08386-1)

Human, Monkey

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A08386-1
100 μg/vial

ABP1 (AOC1) (NM_001091) Human Over-expression Lysate

Human

$628
Cat # LS000026
20 µg, 100 µg

AOC1 Overview

Facts about Amiloride-sensitive amine oxidase [copper-containing].

AOC1 3D structure. Source: alphafold

Amiloride-sensitive amine oxidase [copper-containing] (AOC1)

Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic reactions and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.

Gene Information

Human
Gene Name:	AOC1
Uniprot:	P19801
Entrez:	26

Family

Belongs to:

copper/topaquinone oxidase family

Alternative Names

ABP; ABP1; amiloride binding protein 1 (amine oxidase (copper-containing)); Amiloride-binding protein; amiloride-sensitive amine oxidase [copper-containing]; amiloride-sensitive amine oxidase; AOC1; AOC1DAOamiloride-binding protein-1; DAO1; Diamine Oxidase; EC 1.4.3; EC 1.4.3.22; Histaminase; KAO; Kidney amine oxidase

Molecular Weight

Mass (kDA):
85.378 kDA

Genomic Context


Human

Location:	7q36.1
Sequence:	7; NC_000007.14 (150824875..150861504)

Tissue Specificity

Placenta and kidney.

Subcellular Localizations

Secreted, extracellular space.

Diseases

Edema
Fibrosis
Cystic Fibrosis
Tissue Adhesions
Neoplasms
Malignant Neoplasms
Dysequilibrium Syndrome
Allergic Asthma
Inflammation
Retinopathy Of Prematurity
Asthma
Allergy

Eosinophilia
Wiskott-aldrich Syndrome
Multiple Acyl Coenzyme A Dehydrogenase Deficiency
Instabilities, Chromosomal
Neoplasm Metastasis
Trinucleotide Repeat Expansion
Malignant Tumor Of Colon

Pathways

Endocytosis
Localization
Transport
Cell Division
Cell Cycle
Receptor-mediated Endocytosis
Actin Nucleation
Clathrin-mediated Endocytosis
Auxin Transport
Cell Growth
Chromosome Segregation
Secretion
Glycosylation

Dna Replication
Cytokinesis
Mating
Protein Folding
Virulence
Phagocytosis
Cell Migration

PTMs

Phosphorylation
Ubiquitination
Cleavage
Glycosylation
Methylation
Carboxylation
Deamination

Dephosphorylation
Ribosylation
Biotinylation
Reduction
Farnesylation
Deacetylation
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AOC1

References

PMID: 2217167 by Barbry P., et al. Human kidney amiloride-binding protein: cDNA structure and functional expression.

PMID: 8182053 by Chassande O., et al. The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter.