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- Table of Contents
Facts about AP-4 complex subunit mu-1.
They control the vesicular transport of proteins in different trafficking pathways (PubMed:10436028, PubMed:11139587, PubMed:10066790, PubMed:11802162, PubMed:20230749). AP-4 forms a non clathrin- associated coating on vesicles departing the trans-Golgi network (TGN) and could be involved in the targeting of proteins in the trans-Golgi network (TGN) to the endosomal-lysosomal system (PubMed:11139587, PubMed:20230749).
| Human | |
|---|---|
| Gene Name: | AP4M1 |
| Uniprot: | O00189 |
| Entrez: | 9179 |

| Belongs to: |
|---|
| adaptor complexes medium subunit family |

Adapter-related protein complex 4 mu-1 subunit; adaptor-related protein complex 4, mu 1 subunit; adaptor-related protein complex AP-4 mu4 subunit; AP-4 adapter complex mu subunit; AP-4 complex subunit mu-1; CPSQ3; Mu subunit of AP-4; mu4; MU-4; mu4-adaptin; Mu-adaptin-related protein 2; mu-adaptin-related protein-2; MUARP2; MU-ARP2
Mass (kDA):
49.977 kDA

| Human | |
|---|---|
| Location: | 7q22.1 |
| Sequence: | 7; NC_000007.14 (100101413..100109039) |
Ubiquitous. Highly expressed in testis and lowly expressed in brain and lung.
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Early endosome. Found in soma and dendritic shafts of neuronal cells.





PMID: 9013859 by Wang X., et al. Identification of two new mu-adaptin-related proteins, mu-ARP1 and mu-ARP2.
PMID: 10436028 by Hirst J., et al. Characterization of a fourth adaptor-related protein complex.