ARHGAP21 Antibodies

AND ARHGAP21 ELISA kits, ARHGAP21 Proteins

Many biological assays use antibodies to detect ARHGAP21, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARHGAP21 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARHGAP21 antibodies...

We validate the specificity of these antibodies to ARHGAP21 by testing them on tissues known to express ARHGAP21 positively and negatively. Browse below to find the ARHGAP21 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARHGAP21 Infographic by Boster Bio

All ARHGAP21 Products

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Anti-ARHGAP21 Antibody

Human, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A05828
100 μl/vial

ARHGAP21 Overview

Facts about Rho GTPase-activating protein 21.

ARHGAP21 3D structure. Source: alphafold

Rho GTPase-activating protein 21 (ARHGAP21)

Functions as a GTPase-activating protein (GAP) for RHOA and CDC42.
Downstream partner of ARF1 which may control Golgi apparatus structure and function.

Also necessary for CTNNA1 recruitment to adherens junctions. .

Gene Information

Human
Gene Name:	ARHGAP21
Uniprot:	Q5T5U3
Entrez:	57584

Family

Belongs to:

No superfamily

Alternative Names

DKFZp761L0424; FLJ33323; FLJ90108; KIAA1424; Rho GTPase activating protein 21; rho GTPase-activating protein 10; rho GTPase-activating protein 21; Rho-GTPase activating protein 10; rho-type GTPase-activating protein 21

Molecular Weight

Mass (kDA):
217.462 kDA

Genomic Context


Human

Location:	10p12.1\|10p12.3
Sequence:	10; NC_000010.11 (24583610..24725421, complement)

Tissue Specificity

Widely expressed with higher expression in brain, heart, skeletal muscle and placenta.

Subcellular Localizations

Golgi apparatus membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Localization to the Golgi is dependent on interaction with GTP-bound ARF1.

Diseases

Malignant Neoplasms
Neoplasms
Carcinogenesis
Head And Neck Carcinoma
Carcinoma
Head And Neck Neoplasms
Influenza
Malignant Squamous Cell Neoplasm
Glioblastoma
Brain Neoplasms
Salivary Gland Neoplasms
Neoplasm Metastasis
Disease Of Adrenal Medulla

Malignant Neoplasm Of Kidney
Melanoma
Tumor Progression
Malignant Neoplasm Of Breast
Cardiac Hypertrophy
Glioma
Malignant Neoplasm Of Lung

Interacting Proteins

Arf1
EEF1D
YWHAZ

Pathways

Transport
Cell Proliferation
Cell Migration
Intracellular Transport
Secretory Pathway
Endocytosis
Transferrin Transport
Nuclear Export
Cytoskeleton Organization
Translation

Cell Cycle
Cell Death
Cell Motility
Cell Differentiation
Regulation Of Intracellular Transport

PTMs

Phosphorylation

Sumoylation

Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARHGAP21

References

PMID: 12056806 by Basseres D.S., et al. ARHGAP10, a novel human gene coding for a potentially cytoskeletal Rho-GTPase activating protein.

PMID: 15375573 by Katoh M., et al. Characterization of human ARHGAP10 gene in silico.