ARRDC1 Antibodies

AND ARRDC1 ELISA kits, ARRDC1 Proteins

Many biological assays use antibodies to detect ARRDC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARRDC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARRDC1 antibodies...

We validate the specificity of these antibodies to ARRDC1 by testing them on tissues known to express ARRDC1 positively and negatively. Browse below to find the ARRDC1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARRDC1 Infographic by Boster Bio

All ARRDC1 Products

Product

Figures

Specificity

Applications

Price

Anti-Arrdc1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A16232
100ul

ARRDC1 (NM_152285) Human Over-expression Lysate

Human

$628
Cat # LS092714
100 µg

ARRDC1 Overview

Facts about Arrestin domain-containing protein 1.

ARRDC1 3D structure. Source: alphafold

Arrestin domain-containing protein 1 (ARRDC1)

Functions as an adapter recruiting ubiquitin-protein ligases for their unique substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458).

More commonly, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426). By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).

Gene Information

Human
Gene Name:	ARRDC1
Uniprot:	Q8N5I2
Entrez:	92714

Family

Belongs to:

arrestin family

Alternative Names

Arrestin domain-containing protein 1

Molecular Weight

Mass (kDA):
45.981 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (137605640..137615360)

Subcellular Localizations

Cell membrane. Also found in extracellular vesicles different from exosomes.

Interacting Proteins

WWP2

PTMs

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARRDC1

References

PMID: 21191027 by Rauch S., et al. Multiple interactions between the ESCRT machinery and arrestin- related proteins: implications for PPXY-dependent budding.

PMID: 22315426 by Nabhan J.F., et al. Formation and release of arrestin domain-containing protein 1- mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein.