ATP synthase subunit gamma, mitochondrial (ATP5F1C)

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or intricate V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - comprising the extramembraneous catalytic core, and F(0) - comprising the membrane proton channel, linked together by a central stalk and a peripheral stalk.

During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the intricate F(1) domain and the central stalk which is part of the intricate rotary element.