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- Table of Contents
BCR Antibodies
AND BCR ELISA kits, BCR Proteins
Many biological assays use antibodies to detect BCR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BCR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BCR antibodies...
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BCR Infographic by Boster Bio
All BCR Products
Product
Figures
Specificity
Applications
Price
Anti-Bcr Antibody Picoband®
15 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # PB9988
100 μg/vial
Cat # PB9988
100 μg/vial
Human, Mouse
ELISA
$480
Cat # EKC1058
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1058
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2191
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2191
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2365
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2365
1 kit, containing two 96-well plates and all necessary reagents
Human, Monkey, Mouse
ELISA, IF, IHC, WB
$380
Cat # A00022Y360
100ul
Cat # A00022Y360
100ul
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00022-2
100 μg/vial
Cat # A00022-2
100 μg/vial
BCR Overview
Facts about Breakpoint cluster region protein.
Breakpoint cluster region protein (BCR)
GTPase-activating protein for RAC1 and CDC42.
Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them.Displays serine/threonine kinase activity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | BCR |
| Uniprot: | P11274 |
| Entrez: | 613 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ALL; ALLD22S11; BCR; BCR1; breakpoint cluster region protein; breakpoint cluster region; CMLEC 2.7.11.1; D22S662; PHL; PHLFLJ16453; Renal carcinoma antigen NY-REN-26
Molecular Weight
Mass (kDA):
142.819 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q11.23 |
| Sequence: | 22; NC_000022.11 (23180509..23318037) |
Subcellular Localizations
Cell junction, synapse, postsynaptic density. Cell projection, dendritic spine. Cell projection, axon. Cell junction, synapse.
Diseases
- Leukemia
- Myeloid Leukemia, Chronic
- Myeloid Leukemia
- Philadelphia Chromosome
- Malignant Neoplasms
- Acute Lymphocytic Leukemia
- Neoplasms
- Blast Phase
- Chromosomal Translocation
- Lymphoma
- Lymphoid Leukemia
- Malignant Paraganglionic Neoplasm
- Leukemia, Myelocytic, Acute
Interacting Proteins
- GRB2
- PTPN1
- Sh2d5
- TNKS2
- TP53
Pathways
- Pathogenesis
- Cell Activation
- Cell Development
- Cell Proliferation
- B Cell Activation
- Cell Cycle
- Cell Death
- Immune Response
- Localization
- Interphase
- Cell Growth
- Cell Differentiation
- B Cell Proliferation
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
- Methylation
- Ubiquitination
- Glycosylation
- Oxidation
- Reduction
- Phosphorothioation
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BCR
bosterbio.com/bosterbio-gene-info-cards/BCR
References
PMID: 3285291 by Lifshitz B., et al. bcr genes and transcripts.
PMID: 7665185 by Chissoe S.L., et al. Sequence and analysis of the human ABL gene, the BCR gene, and regions involved in the Philadelphia chromosomal translocation.