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- Table of Contents
BMP4 Antibodies
AND BMP4 ELISA kits, BMP4 Proteins
Many biological assays use antibodies to detect BMP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BMP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BMP4 antibodies...
Designing a Western blot for BMP4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the BMP4 Western Blot GuideBMP4 Infographic by Boster Bio
All BMP4 Products
Product
Figures
Specificity
Applications
Price
Mouse BMP-4 ELISA Kit PicoKine®
2 Citations
Mouse
ELISA
$499
Cat # EK0316
96 wells/kit, with removable strips.
Cat # EK0316
96 wells/kit, with removable strips.
Anti-BMP4 Rabbit Monoclonal Antibody
2 Citations
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00321
100 μl
Cat # M00321
100 μl
Swine
Cell Culture
$154
Cat # PROTA7LJT9
5ug,20ug
Cat # PROTA7LJT9
5ug,20ug
Mouse
Cell Culture
$77
Cat # PROTP21275-1
5ug,20ug,100ug
Cat # PROTP21275-1
5ug,20ug,100ug
Human
Cell Culture
$77
Cat # PROTP12644-5
5ug,20ug,100ug
Cat # PROTP12644-5
5ug,20ug,100ug
Monkey
ELISA
$499
Cat # EK0314-PR
96 wells/kit, with removable strips.
Cat # EK0314-PR
96 wells/kit, with removable strips.
Bovine
ELISA
$499
Cat # EK0314-BV
96 wells/kit, with removable strips.
Cat # EK0314-BV
96 wells/kit, with removable strips.
BMP4 Overview
Facts about Bone morphogenetic protein 4.
Bone morphogenetic protein 4 (BMP4)
Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair.
Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | BMP4 |
| Uniprot: | P12644 |
| Entrez: | 652 |
Family
| Belongs to: |
|---|
| TGF-beta family |
Alternative Names
BMP2B; BMP-2B; BMP2B1; BMP2BMCOPS6; BMP4; BMP-4; Bone morphogenetic protein 2B; bone morphogenetic protein 4; DVR4; MCOPS6; OFC11; ZYME
Molecular Weight
Mass (kDA):
46.555 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q22.2 |
| Sequence: | 14; NC_000014.9 (53949736..53956891, complement) |
Tissue Specificity
Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
Subcellular Localizations
Secreted, extracellular space, extracellular matrix.
Diseases
- Malignant Neoplasms
- Neoplasms
- Crest Syndrome
- Nervousness
- Congenital Abnormality
- Carcinoma
- Tissue Adhesions
- Leukemia
- Inflammation
- Tumor Angiogenesis
- Pituitary Diseases
- Fracture
- Hyperplasia
Interacting Proteins
- BMPR1A
Pathways
- Cell Proliferation
- Cell Differentiation
- Gastrulation
- Regeneration
- Pathogenesis
- Cell Death
- Secretion
- Localization
- Ossification
- Osteoblast Differentiation
- Neurogenesis
- Cell Cycle
- Angiogenesis
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Glycosylation
- Demethylation
- Ubiquitination
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BMP4
bosterbio.com/bosterbio-gene-info-cards/BMP4
References
PMID: 3201241 by Wozney J.M., et al. Novel regulators of bone formation: molecular clones and activities.
PMID: 9701626 by Shore E.M., et al. The human bone morphogenetic protein 4 (BMP-4) gene: molecular structure and transcriptional regulation.
8 Publications of Boster BMP4 Antibodies & ELISA Kits
- PubMed ID: 10.3892/ijmm.2016.2636, Mechanical strain promotes osteoblastic differentiation through integrin-β1-med...
- PubMed ID: 10.3892/etm.2015.2391, Expression of β-site APP-cleaving enzyme 1 in the hippocampal tissue of an insu...
- PubMed ID: 10.1080/00365520902998661, Acid and bile salt up-regulate BMP4 expression in human esophageal epithelium ce...
- PubMed ID: 10.1016/S0020-1383(17)30774-X, Bone intramedullary reaming grafts the fracture site with CD146+ skeletal progen...
- PubMed ID: 10.1016/j.biomaterials.2021.121260, An improved osseointegration of metal implants by pitavastatin loaded multilayer...
- PubMed ID: 29674622, Chen WY, Yang JL, Wu YH, Li LC, Li RF, Chang YT, Dai LH, Wang WC, Chang YJ. Exp ...
- PubMed ID: 16336834, Fu Jr, Liu Wl, Zhou Yf, Zhou Jf, Sun Hy, Luo L, Zhang H, Xu Hz. Chin Med J (Engl...
- PubMed ID: 25709905, Wang Q, Xue Ml, Zhao Gq, Liu Mg, Ma Yn, Ma Y. Int J Ophthalmol. 2015 Feb 18;8(1)...
*More publications can be found for each product on its corresponding product page