BTN3A1 Antibodies

AND BTN3A1 ELISA kits, BTN3A1 Proteins

Many biological assays use antibodies to detect BTN3A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BTN3A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BTN3A1 antibodies...

We validate the specificity of these antibodies to BTN3A1 by testing them on tissues known to express BTN3A1 positively and negatively. Browse below to find the BTN3A1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for BTN3A1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the BTN3A1 IHC Guide

BTN3A1 Infographic by Boster Bio

All BTN3A1 Products

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Product

Figures

Specificity

Applications

Price

BTN3A1 (NM_007048) Human Over-expression Lysate

BTN3A1 Human Over-expression Lysates NM_001145009

Human

$960
Cat # LS011119
20 µg, 100 µg

Anti-BTN3A1/2/3 Antibody

Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200

Human

ELISA, IF, IHC

$399
Cat # A04257
100μl

Human CD277/BTN3A1 Recombinant Protein

SDS-PAGE

$293
Cat # PROTO00481
Starting from 10ug

BTN3A1 Overview

Facts about Butyrophilin subfamily 3 member A1.

BTN3A1 3D structure. Source: alphafold

Butyrophilin subfamily 3 member A1 (BTN3A1)

Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells.

Regulates the release of cytokines and IFNG by triggered T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

Gene Information

Human
Gene Name:	BTN3A1
Uniprot:	O00481
Entrez:	11119

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

BT3.1; BTF5; BTN3A1; butyrophilin, subfamily 3, member A1; CD277; dJ45P21.3 (butyrophilin, subfamily 3, member A1)

Molecular Weight

Mass (kDA):
57.677 kDA

Genomic Context


Human

Location:	6p22.2
Sequence:	6; NC_000006.12 (26402269..26415216)

Tissue Specificity

Detected on T-cells, natural killer cells, dendritic cells and macrophages (at protein level). Ubiquitous. Highly expressed in heart, pancreas and lung, Moderately expressed in placenta, liver and muscle.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Neoplasms
Cell Transformation, Neoplastic
Malignant Neoplasms
Emotional Distress
Common Neoplasm
Malignant Neoplasm Of Ovary
Epithelial Ovarian Cancer

Ovarian Neoplasm
Carcinoma

Interacting Proteins

PPL
TFF1

Pathways

Cell Activation
Cell Proliferation
Cytokine Production
Lactation
Secretion

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BTN3A1

References

PMID: 9382921 by Tazi-Ahnini R., et al. Cloning, localization, and structure of new members of the butyrophilin gene family in the juxta-telomeric region of the major histocompatibility complex.

PMID: 9149941 by Ruddy D.A., et al. A 1.1-Mb transcript map of the hereditary hemochromatosis locus.