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- Table of Contents
CAD protein Antibodies
AND CAD ELISA kits, CAD protein Proteins
Many biological assays use antibodies to detect CAD protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CAD protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CAD protein antibodies...
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CAD Infographic by Boster Bio
All CAD Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M00463-1
100 μl/vial
Cat # M00463-1
100 μl/vial
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A00463-4
100 μg/vial
Cat # A00463-4
100 μg/vial
CAD Overview
Facts about CAD protein.
CAD protein (CAD)
This protein is a"combination" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase). .
Gene Information
| Human | |
|---|---|
| Gene Name: | CAD |
| Uniprot: | P27708 |
| Entrez: | 790 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CAD protein; CAD trifunctional protein; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, anddihydroorotase; EC 2.1.3.2; EC 3.5.2.3; EC 6.3.5; EC 6.3.5.5; multifunctional protein CAD
Molecular Weight
Mass (kDA):
242.984 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p23.3 |
| Sequence: | 2; NC_000002.12 (27217369..27243943) |
Subcellular Localizations
Cytoplasm. Nucleus. Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth.
Diseases
- Malignant Neoplasms
- Tissue Adhesions
- Sialodacryoadenitis Of Rat
- Neoplasms
- Shigella Infections
- Carcinoma
- Kyphosis Deformity Of Spine
- Cell Invasion
- Anemia
- Tumor Angiogenesis
- Yersinia Infections
- Disease Caused By Shigella Flexneri
- Infective Disorder
Pathways
- Segmentation
- Muscle Contraction
- Smooth Muscle Contraction
- Virulence
- Translation
- Cell Cycle
- Pathogenesis
- Transport
- Cell Proliferation
- Glycosylation
- Regulation Of Smooth Muscle Contraction
- Gastrulation
- Localization
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Decarboxylation
Research Areas
- Apoptosis
- Cancer
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAD
bosterbio.com/bosterbio-gene-info-cards/CAD
References
PMID: 8619816 by Iwahana H., et al. Molecular cloning of a human cDNA encoding a trifunctional enzyme of carbamoyl-phosphate synthetase-aspartate transcarbamoylase- dihydroorotase in de Novo pyrimidine synthesis.
PMID: 1979741 by Davidson J.N., et al. Organization and nucleotide sequence of the 3' end of the human CAD gene.
1 Publications of Boster CAD protein Antibodies & ELISA Kits
- PubMed ID: 28656299, Quan, J., Du, Q., Hou, Y., Wang, Z., & Zhang, J. (2017). Utilization of E-cadher...
*More publications can be found for each product on its corresponding product page