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C-C motif chemokine 13 Antibodies
AND CCL13 ELISA kits, C-C motif chemokine 13 Proteins
Many biological assays use antibodies to detect C-C motif chemokine 13, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-C motif chemokine 13 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-C motif chemokine 13 antibodies...
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CCL13 Infographic by Boster Bio
All CCL13 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0809
96 wells/kit, with removable strips.
Cat # EK0809
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK0809
96 wells/kit, with removable strips.
Cat # FEK0809
96 wells/kit, with removable strips.
CCL13 Overview
Facts about C-C motif chemokine 13.
C-C motif chemokine 13 (CCL13)
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors.
Plays a role in the accumulation of leukocytes at either side of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Gene Information
| Human | |
|---|---|
| Gene Name: | CCL13 |
| Uniprot: | Q99616 |
| Entrez: | 6357 |
Family
| Belongs to: |
|---|
| intercrine beta (chemokine CC) family |
Alternative Names
C-C motif chemokine 13; CCL13; chemokine (C-C motif) ligand 13; CKb10; MCP4; MCP-4; MCP-4Monocyte chemoattractant protein 4; MGC17134; NCC-1Monocyte chemotactic protein 4; NCC1Small-inducible cytokine A13; new CC chemokine 1; SCYA13CK-beta-10; SCYL1; small inducible cytokine subfamily A (Cys-Cys), member 13
Molecular Weight
Mass (kDA):
10.986 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q12 |
| Sequence: | 17; NC_000017.11 (34356480..34358610) |
Tissue Specificity
Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells.
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Cholangiocarcinoma
- Asthma
- Hepatitis
- Allergy
- Dermatitis, Atopic
- Hepatitis B
- Rheumatoid Arthritis
- Arthritis
- Rhinorrhea
- Sclerosis
- Dermatitis
- Neoplasms
Interacting Proteins
- CCL21
- CCL26
- CCL5
- CXCL10
- CXCL11
- CXCL12
- PF4
- XCL1
Pathways
- Chemotaxis
- Pathogenesis
- Secretion
- Immune Response
- Cell Migration
- Cell Proliferation
- Chemokine Production
- Leukocyte Migration
- Dna Repair
- Receptor Internalization
- Proteolysis
- Translation
- Eosinophil Migration
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCL13
bosterbio.com/bosterbio-gene-info-cards/CCL13
References
PMID: 8955214 by Garcia-Zepeda E.A., et al. Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3.
PMID: 8642349 by Uguccioni M., et al. Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin.