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- Table of Contents
C-C motif chemokine 25 Antibodies
AND CCL25 ELISA kits, C-C motif chemokine 25 Proteins
Many biological assays use antibodies to detect C-C motif chemokine 25, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-C motif chemokine 25 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-C motif chemokine 25 antibodies...
Designing an IHC experiment for C-C motif chemokine 25? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CCL25 IHC GuideCCL25 Infographic by Boster Bio
All CCL25 Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA
$499
Cat # FEK1424
96 wells/kit, with removable strips.
Cat # FEK1424
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1424
96 wells/kit, with removable strips.
Cat # EK1424
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK1145
96 wells/kit, with removable strips.
Cat # FEK1145
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK1145
96wells/kit, with removable strips.
Cat # EK1145
96wells/kit, with removable strips.
CCL25 Overview
Facts about C-C motif chemokine 25.
C-C motif chemokine 25 (CCL25)
Potentially involved in T-cell development. Recombinant protein reveals chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils.
Binds to CCR9. Isoform 2 is an antagonist of isoform 1.
Gene Information
| Human | |
|---|---|
| Gene Name: | CCL25 |
| Uniprot: | O15444 |
| Entrez: | 6370 |
Family
| Belongs to: |
|---|
| intercrine beta (chemokine CC) family |
Alternative Names
C-C motif chemokine 25; CCL25; chemokine (C-C motif) ligand 25; Chemokine TECK; Ck beta-15; Ckb15; SCYA25TECKvar; small inducible cytokine subfamily A (Cys-Cys), member 25; Small-inducible cytokine A25; TECK; TECKMGC150327; thymus expressed chemokine; Thymus-expressed chemokine
Molecular Weight
Mass (kDA):
16.609 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.2 |
| Sequence: | 19; NC_000019.10 (8052318..8062663) |
Tissue Specificity
Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Subcellular Localizations
Secreted.
Diseases
- Cholangiocarcinoma
- Inflammation
- Tissue Adhesions
- Inflammatory Bowel Diseases
- Malignant Neoplasms
- Intestinal Diseases
- Neoplasms
- Neoplasm Metastasis
- Crohn Disease
- Colitis
- Cell Invasion
- Disease Of Adrenal Medulla
Interacting Proteins
- CCL17
- CCL5
- CXCL12
- PF4
- PF4V1
Pathways
- Chemotaxis
- Localization
- Cell Migration
- Pathogenesis
- Cell Development
- Cell Adhesion
- Immune Response
- Leukocyte Migration
- Cell Proliferation
- Inflammatory Response
- Lymphocyte Migration
- Cell Activation
- Secretion
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCL25
bosterbio.com/bosterbio-gene-info-cards/CCL25
References
PMID: 9285413 by Vicari A.P., et al. TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development.
PMID: 10229797 by Zaballos A., et al. Identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK.