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- Table of Contents
CDC5L Antibodies
AND CDC5L ELISA kits, CDC5L Proteins
Many biological assays use antibodies to detect CDC5L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDC5L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDC5L antibodies...
Designing a Western blot for CDC5L? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CDC5L Western Blot GuideCDC5L Infographic by Boster Bio
All CDC5L Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M03797
100 μl
Cat # M03797
100 μl
CDC5L Overview
Facts about Cell division cycle 5-like protein.
Cell division cycle 5-like protein (CDC5L)
DNA-binding protein involved in cell cycle control. May act as a transcription activator.
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Gene Information
| Human | |
|---|---|
| Gene Name: | CDC5L |
| Uniprot: | Q99459 |
| Entrez: | 988 |
Family
| Belongs to: |
|---|
| CEF1 family |
Alternative Names
CDC5 (cell division cycle 5, S. pombe, homolog)-like; CDC5 cell division cycle 5-like (S. pombe); CDC5; Cdc5-like protein; Cdc5-related protein; CEF1; cell division cycle 5-like protein; dJ319D22.1 (CDC5-like protein); dJ319D22.1; hCDC5; KIAA0432; PCDC5RPCDC5-LIKE; Pombe cdc5-related protein
Molecular Weight
Mass (kDA):
92.251 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.1 |
| Sequence: | 6; NC_000006.12 (44387706..44450425) |
Tissue Specificity
Ubiquitously expressed in both fetal and adult tissues.
Subcellular Localizations
Nucleus. Nucleus speckle. Cytoplasm. May shuttle between cytoplasm and nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Bone Neoplasms
- Osteosarcoma
- Malignant Bone Neoplasm
- Cell Transformation, Neoplastic
- Malignant Paraganglionic Neoplasm
- Sclerosis
- Renal Dysplasia
- Obstruction Of Pelviureteric Junction
- Werner Syndrome
Interacting Proteins
- ATR
- BCAS2
- CTNNBL1
- GOLGA2
- GOLGA8DP
- GOLGA8F
- HNRNPC
- HNRNPM
- HOOK1
- KANSL1
Pathways
- Cell Cycle
- Cell Division
- Dna Repair
- Localization
- Aging
- Mrna Splicing
- Transport
- Cell Cycle Checkpoint
- Proteolysis
- Nuclear Transport
- Blastocyst Formation
- Translation
- Interphase
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDC5L
bosterbio.com/bosterbio-gene-info-cards/CDC5L
References
PMID: 9038199 by Bernstein H.S., et al. Pombe Cdc5-related protein. A putative human transcription factor implicated in mitogen-activated signaling.
PMID: 9598309 by Groenen P.M.A., et al. Rearrangement of the human CDC5L gene by a t(6;19)(p21;q13.1) in a patient with multicystic renal dysplasia.