CDIPT Antibodies

AND CDIPT ELISA kits, CDIPT Proteins

Many biological assays use antibodies to detect CDIPT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDIPT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDIPT antibodies...

We validate the specificity of these antibodies to CDIPT by testing them on tissues known to express CDIPT positively and negatively. Browse below to find the CDIPT antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDIPT Infographic by Boster Bio

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CDIPT (NM_006319) Human Over-expression Lysate

Human

$628
Cat # LS010423
20 µg, 100 µg

CDIPT Overview

Facts about CDP-diacylglycerol--inositol 3-phosphatidyltransferase.

CDIPT 3D structure. Source: alphafold

CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT)

Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) in addition to PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content.

The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is closely bound to the enzyme. .

Gene Information

Human
Gene Name:	CDIPT
Uniprot:	O14735
Entrez:	10423

Family

Belongs to:

CDP-alcohol phosphatidyltransferase class-I family

Alternative Names

CDP-diacylglycerol--inositol 3-phosphatidyltransferase; EC 2.7.8.11; Phosphatidylinositol synthase; PI synthase; PIS1MGC1328; PISCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositolsynthase); PtdIns synthase

Molecular Weight

Mass (kDA):
23.539 kDA

Genomic Context


Human

Location:	16p11.2
Sequence:	16; NC_000016.10 (29858357..29863226, complement)

Tissue Specificity

Detected in placenta (at protein level). Widely expressed. Higher expression in adult liver and skeletal muscle, slightly lower levels seen in pancreas, kidney, lung, placenta, brain, heart, leukocyte, colon, small intestine, ovary, testis, prostate, thymus and spleen. In fetus, expressed in kidney, liver, lung and brain.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane.

Diseases

Carcinoma
Pituitary Diseases
Hyperglycemia
Pituitary Neoplasms
Neoplasms
Malignant Squamous Cell Neoplasm
Complications Of Diabetes Mellitus
Liver Diseases
Hypokinesia
Mouth Neoplasms
Malignant Neoplasm Of Mouth
Malignant Neoplasms
Leukoplakia, Oral

Retinoblastoma
Malnutrition
Infectious Mononucleosis
Glioma
Malignant Neoplasm Of Lung
Hyperkeratosis
Endoplasmic Reticulum Stress

Interacting Proteins

RTN3
SDCBP

Pathways

Transport
Cell Proliferation
Cell Cycle
Cell Growth
Cell Adhesion
Hyperphosphorylation
Insulin Secretion
G1 Phase
Localization
Cell Death

Regulation Of Cell Growth
Pathogenesis
Regulation Of Insulin Secretion
Cell-cell Adhesion
Secretion

PTMs

Phosphorylation

Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDIPT

References

PMID: 9407135 by Lykidis A., et al. The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content.

PMID: 8110188 by Antonsson B.E.; Purification and characterization of phosphatidylinositol synthase from human placenta.