Corneodesmosin Antibodies

AND CDSN ELISA kits, Corneodesmosin Proteins

Many biological assays use antibodies to detect Corneodesmosin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Corneodesmosin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Corneodesmosin antibodies...

We validate the specificity of these antibodies to Corneodesmosin by testing them on tissues known to express CDSN positively and negatively. Browse below to find the CDSN antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDSN Infographic by Boster Bio

All CDSN Products

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Product

Figures

Specificity

Applications

Price

Anti-Corneodesmosin CDSN Antibody

Western blot analysis of extracts of various cell lines, using CDSN antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A04329
100ul

Human CDSN ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2160
96 wells/kit, with removable strips.

Corneodesmosin (CDSN) (NM_001264) Human Over-expression Lysate

Human

$628
Cat # LS001041
20 µg, 100 µg

CDSN Overview

Facts about Corneodesmosin.

CDSN 3D structure. Source: alphafold

Corneodesmosin (CDSN)

Important for the epidermal barrier integrity. .

Gene Information

Human
Gene Name:	CDSN
Uniprot:	Q15517
Entrez:	1041

Family

Belongs to:

No superfamily

Alternative Names

CDSN; Corneodesmosin; D6S586E; differentiated keratinocyte S protein; HTSS; S protein; S

Molecular Weight

Mass (kDA):
51.522 kDA

Genomic Context


Human

Location:	6p21.33
Sequence:	6; NC_000006.12 (31115087..31120446, complement)

Tissue Specificity

Exclusively expressed in skin.

Subcellular Localizations

Secreted. Found in corneodesmosomes, the intercellular structures that are involved in desquamation.

Diseases

Psoriasis
Dysequilibrium Syndrome
Dermatologic Disorders
Tissue Adhesions
Hypotrichosis
Exfoliative Dermatitis
Hypotrichosis Simplex
Ichthyosis Linearis Circumflexa
Dermatitis, Atopic
Dermatitis
Pigmentation Disorders
Ichthyoses

Ichthyosis Vulgaris
Arthritis, Psoriatic
Pruritus
Lichen Disease
Lichen Planus
Autoimmune Diseases

Pathways

Pathogenesis
Proteolysis
Keratinocyte Differentiation
Cell-cell Adhesion
Cornification
Localization
Keratinocyte Proliferation
Secretion
Transport

Immune Response
Skin Development
Inflammatory Response
Corneocyte Desquamation

PTMs

Cleavage

Deglycosylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDSN

References

PMID: 8415725 by Zhou Y., et al. Identification in the HLA class I region of a gene expressed late in keratinocyte differentiation.

PMID: 9712893 by Guerrin M., et al. Expression cloning of human corneodesmosin proves its identity with the product of the S gene and allows improved characterization of its processing during keratinocyte differentiation.