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Part of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function.
|Sequence:||16; NC_000016.10 (67828157..67847693, complement)|
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. Localizes to the inner kinetochore, and may connect it to the outer kinetochore via its N-terminus.