Centromere protein T Antibodies

AND CENPT ELISA kits, Centromere protein T Proteins

Many biological assays use antibodies to detect Centromere protein T, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Centromere protein T in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Centromere protein T antibodies...

We validate the specificity of these antibodies to Centromere protein T by testing them on tissues known to express CENPT positively and negatively. Browse below to find the CENPT antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CENPT Infographic by Boster Bio

All CENPT Products

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Price

Anti-Centromere protein T CENPT Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A06574
100ul

CENPT (NM_025082) Human Recombinant Protein

Coomassie blue staining of purified CENPT protein

$1249
Cat # PROTQ96BT3
20 µg

CENPT (NM_025082) Human Over-expression Lysate

Human

$628
Cat # LS080152
20 µg, 100 µg

CENPT Overview

Facts about Centromere protein T.

CENPT 3D structure. Source: alphafold

Centromere protein T (CENPT)

The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complicated and can be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome- associated complex that binds specifically to histone H3- containing nucleosomes in the centromere, instead of nucleosomes containing CENPA.

Part of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function.

Gene Information

Human
Gene Name:	CENPT
Uniprot:	Q96BT3
Entrez:	80152

Family

Belongs to:

CENP-T/CNN1 family

Alternative Names

C16orf56; CENP-Tchromosome 16 open reading frame 56; centromere protein T; FLJ13111; FLJ43376; ICEN22; Interphase centromere complex protein 22

Molecular Weight

Mass (kDA):
60.423 kDA

Genomic Context


Human

Location:	16q22.1
Sequence:	16; NC_000016.10 (67828157..67847693, complement)

Subcellular Localizations

Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. Localizes to the inner kinetochore, and may connect it to the outer kinetochore via its N-terminus.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CENPT

References

PMID: 16716197 by Izuta H., et al. Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.

PMID: 16622419 by Foltz D.R., et al. The human CENP-A centromeric nucleosome-associated complex.