Cofilin-2 (CFL2)

Controls reversibly actin polymerization and depolymerization in a pH-sensitive method. Its F-actin depolymerization activity is regulated by association with CSPR3 (PubMed:19752190).

It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It's the major component of intranuclear and cytoplasmic actin rods.