CGB3 Antibodies

AND CGB3 ELISA kits, CGB3 Proteins

Many biological assays use antibodies to detect CGB3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CGB3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CGB3 antibodies...

We validate the specificity of these antibodies to CGB3 by testing them on tissues known to express CGB3 positively and negatively. Browse below to find the CGB3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CGB3 Infographic by Boster Bio

All CGB3 Products

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Product

Figures

Specificity

Applications

Price

Anti-CGB5 CGB3 Antibody

Western blot analysis of extracts of various cell lines, using CGB5 antibody at 1:1000 dilution

Human

$405
Cat # A13820
100ul

Human CGB3 Recombinant Protein

SDS-PAGE

$293
Cat # PROTP0DN86
Starting from 10ug

Anti-hCG beta (CGB3) Mouse Monoclonal Antibody [Clone ID: OTI12H5]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CGB (Right lane) cDNA for 48 hrs and lysed

Human

IHC, WB

$523
Cat # M13820-1
100 µl

CGB3 Overview

Facts about Choriogonadotropin subunit beta 3.

CGB3 3D structure. Source: alphafold

Choriogonadotropin subunit beta 3 (CGB3)

HCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those from the pituitary gonadotropin hormones (LH, FSH and TSH).

The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation.

Gene Information

Human
Gene Name:	CGB3
Uniprot:	P0DN86
Entrez:	1082

Family

Belongs to:

glycoprotein hormones subunit beta family

Alternative Names

CGB; CGB3; CGB3choriogonadotropin subunit beta; CGB5; CGB7; CGB8; CG-Beta; Choriogonadotropin Subunit Beta; Chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; Chorionic Gonadotropin beta Chain; chorionic gonadotropin beta subunit; chorionic gonadotropin, beta polypeptide; hCGB

Molecular Weight

Mass (kDA):
17.739 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (49022869..49024375, complement)

Tissue Specificity

High expression in the placenta throughout pregnancy.

Subcellular Localizations

Secreted.

Diseases

Infection By Cryptococcus Neoformans
Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Infective Disorder
Acquired Immunodeficiency Syndrome
Aids-related Opportunistic Infections
Malignant Paraganglionic Neoplasm
Carcinoma
Endometrial Polyp
Disease Of Adrenal Medulla

Pituitary Diseases
Cell Invasion
Meningitis
Immunologic Deficiency Syndromes
Hemorrhage
Pancreatitis
Fibrosis

Pathways

Secretion
Localization
Gene Conversion
Mating
Glycosylation
Pathogenesis
Cell Cycle
Cell Migration
Progesterone Secretion
Colony Morphology
Catecholamine Secretion
Reflex
Fermentation

Cell Differentiation
Regulated Secretory Pathway
Exocytosis
Gastric Acid Secretion
Sulfation
Secretory Pathway
Lactation

PTMs

Cleavage
Nitration

Phosphorylation
Biotinylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CGB3

References

PMID: 6774259 by Fiddes J.C., et al. The cDNA for the beta-subunit of human chorionic gonadotropin suggests evolution of a gene by readthrough into the 3'-untranslated region.

PMID: 6690982 by Talmadge K., et al. Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone.