Neural cell adhesion molecule L1-like protein (CHL1)

Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death.

Plays a role in neuronal placement of pyramidal neurons and in regulation of both the amount of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development.