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Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1 (PubMed:23596212). NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), likely by supplying electrons for reduction during radical cofactor maturation from the catalytic small subunit (By similarity).
|Sequence:||16; NC_000016.10 (57428169..57447528, complement)|
Ubiquitously expressed. Highly expressed in heart, liver and pancreas.
Cytoplasm. Nucleus. Mitochondrion intermembrane space.