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- Table of Contents
Facts about Anamorsin.
Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1 (PubMed:23596212). NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), likely by supplying electrons for reduction during radical cofactor maturation from the catalytic small subunit (By similarity).
Human | |
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Gene Name: | CIAPIN1 |
Uniprot: | Q6FI81 |
Entrez: | 57019 |
Belongs to: |
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anamorsin family |
Anamorsin; cytokine induced apoptosis inhibitor 1; Cytokine-induced apoptosis inhibitor 1; DRE2; Fe-S cluster assembly protein DRE2 homolog; predicted protein of HQ0915,2810413N20Rik; PRO0915
Mass (kDA):
33.582 kDA
Human | |
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Location: | 16q21 |
Sequence: | 16; NC_000016.10 (57428169..57447528, complement) |
Ubiquitously expressed. Highly expressed in heart, liver and pancreas.
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
PMID: 11483580 by Yu Y., et al. Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs.
PMID: 14970183 by Shibayama H., et al. Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis.