CNGA4 Antibodies

AND CNGA4 ELISA kits, CNGA4 Proteins

Many biological assays use antibodies to detect CNGA4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CNGA4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CNGA4 antibodies...

We validate the specificity of these antibodies to CNGA4 by testing them on tissues known to express CNGA4 positively and negatively. Browse below to find the CNGA4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CNGA4 Infographic by Boster Bio

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CNGA4 (NM_001037329) Human Over-expression Lysate

Human

$960
Cat # LS001262
20 µg, 100 µg

CNGA4 Overview

Facts about Cyclic nucleotide-gated cation channel alpha-4.

CNGA4 3D structure. Source: alphafold

Cyclic nucleotide-gated cation channel alpha-4 (CNGA4)

Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of the channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation.

By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity). .

Gene Information

Human
Gene Name:	CNGA4
Uniprot:	Q8IV77
Entrez:	1262

Family

Belongs to:

cyclic nucleotide-gated cation channel (TC 1.A.1.5) family

Alternative Names

Cyclic nucleotide-gated cation channel alpha-4

Molecular Weight

Mass (kDA):
65.999 kDA

Genomic Context


Human

Location:	11p15.4
Sequence:	11; NC_000011.10 (6234713..6245924)

Subcellular Localizations

Membrane; Multi-pass membrane protein.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNGA4

References

PMID: 15195096 by Bradley J., et al. Calmodulin permanently associates with rat olfactory CNG channels under native conditions.

PMID: 17032767 by Brady J.D., et al. Interplay between PIP3 and calmodulin regulation of olfactory cyclic nucleotide-gated channels.