Carboxypeptidase Q Antibodies

AND CPQ ELISA kits, Carboxypeptidase Q Proteins

Many biological assays use antibodies to detect Carboxypeptidase Q, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Carboxypeptidase Q in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Carboxypeptidase Q antibodies...

We validate the specificity of these antibodies to Carboxypeptidase Q by testing them on tissues known to express CPQ positively and negatively. Browse below to find the CPQ antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CPQ Infographic by Boster Bio

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PGCP (CPQ) (NM_016134) Human Over-expression Lysate

Human

$628
Cat # LS010404
20 µg, 100 µg

CPQ Overview

Facts about Carboxypeptidase Q.

CPQ 3D structure. Source: alphafold

Carboxypeptidase Q (CPQ)

Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids.

May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor. .

Gene Information

Human
Gene Name:	CPQ
Uniprot:	Q9Y646
Entrez:	10404

Family

Belongs to:

peptidase M28 family

Alternative Names

aminopeptidase; CPQ; EC 3.4.17; EC 3.4.17.-; Hls2; Lal-1; PGCP; plasma glutamate carboxypeptidase

Molecular Weight

Mass (kDA):
51.888 kDA

Genomic Context


Human

Location:	8q22.1
Sequence:	8; NC_000008.11 (96645242..97143501)

Tissue Specificity

Mainly detected in blood plasma. Abundant in placenta and kidney. Present at low level in muscles, liver and skin fibroblasts. Not detected in brain or white blood cells (at protein level).

Subcellular Localizations

Endoplasmic reticulum. Golgi apparatus. Lysosome. Secreted. Secretion is stimulated by TSH/thyroid-stimulating hormone, INS/insulin and SST/somatostatin.

Diseases

Malocclusion
Dental Caries
Anxiety Disorders
Intrahepatic Cholangiocarcinoma
Pain
Cleft Lip
Dental Fluorosis, Acquired
Malignant Neoplasms
Mouth Diseases
Cleft Palate
Developmental Disabilities

Neoplasms
Mental Disorders
Tooth Injuries
Myeloproliferative Syndrome, Transient
Toothache
Temporomandibular Joint Disorders

Pathways

Translation
Fertilization

PTMs

Deamination

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CPQ

References

PMID: 10206990 by Gingras R., et al. Purification, cDNA cloning, and expression of a new human blood plasma glutamate carboxypeptidase homologous to N-acetyl-aspartyl- alpha-glutamate carboxypeptidase/prostate-specific membrane antigen.

PMID: 12675526 by Dolenc I., et al. Purification and primary structure determination of human lysosomal dipeptidase.