Cytochrome P450 2W1 Antibodies

AND CYP2W1 ELISA kits, Cytochrome P450 2W1 Proteins

Many biological assays use antibodies to detect Cytochrome P450 2W1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 2W1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 2W1 antibodies...

We validate the specificity of these antibodies to Cytochrome P450 2W1 by testing them on tissues known to express CYP2W1 positively and negatively. Browse below to find the CYP2W1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CYP2W1 Infographic by Boster Bio

All CYP2W1 Products

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Specificity

Applications

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Anti-Cytochrome P450 2W1 CYP2W1 Antibody

Western Blot analysis of various cells using CYP2W1 Polyclonal Antibody

Western blot analysis of the lysates from HT-29 cells using CDH2 antibody

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using Cytochrome P450 2W1 Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A06299-1
100ul

CYP2W1 (NM_017781) Human Over-expression Lysate

Human

$628
Cat # LS054905
20 µg, 100 µg

Anti-CYP2W1 Antibody Picoband®

Western blot analysis of CYP2W1 using anti-CYP2W1 antibody (A06299-2)

IHC analysis of CYP2W1 using anti-CYP2W1 antibody (A06299-2)

Human

IHC, WB

$370
Cat # A06299-2
100 μg/vial

CYP2W1 Overview

Facts about Cytochrome P450 2W1.

CYP2W1 3D structure. Source: alphafold

Cytochrome P450 2W1 (CYP2W1)

Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:16551781, PubMed:24278521). Active also in the metabolism of indoline substrates and can activate aflatoxin B1 into cytotoxic products (PubMed:20805301).

Furthermore, it is apparently involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743). .

Gene Information

Human
Gene Name:	CYP2W1
Uniprot:	Q8TAV3
Entrez:	54905

Family

Belongs to:

cytochrome P450 family

Alternative Names

CYPIIW1; cytochrome P450 2W1; cytochrome P450, family 2, subfamily W, polypeptide 1; EC 1.14.14.-; EC 1.14.14.1; EC 1.14.14.5; FLJ20359; MGC34287

Molecular Weight

Mass (kDA):
53.844 kDA

Genomic Context


Human

Location:	7p22.3
Sequence:	7; NC_000007.14 (983155..989640)

Tissue Specificity

Very low levels are detected in fetal and adult tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors.

Subcellular Localizations

Endoplasmic reticulum lumen. Cell membrane. About 8% are expressed on the cell surface.

Diseases

Malignant Neoplasms
Neoplasms
Colorectal Cancer
Colorectal Neoplasms
Malignant Tumor Of Colon
Malignant Neoplasm Of Breast
Colonic Neoplasms
Mammary Neoplasms
Carcinogenesis
Cholangiocarcinoma
Stomach Neoplasms
Stage, Colon Cancer
Non-neoplastic Disorder

Melanoma
Hypoxia
Lung Diseases
Neoplasm Invasiveness
Malignant Neoplasm Of Lung
Carcinoma
Hyperglycemia

Pathways

Methylation
Transport
Reverse Transcription
Glycosylation
Localization
Demethylation

PTMs

Demethylation
Oxidation
Methylation

Biotinylation
Reduction
Hydroxylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP2W1

References

PMID: 16426568 by Karlgren M., et al. Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.

PMID: 16551781 by Wu Z.L., et al. Recombinant enzymes overexpressed in bacteria show broad catalytic specificity of human cytochrome P450 2W1 and limited activity of human cytochrome P450 2S1.