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- Table of Contents
C-C motif chemokine 19 Antibodies
AND CCL19 ELISA kits, C-C motif chemokine 19 Proteins
Many biological assays use antibodies to detect C-C motif chemokine 19, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-C motif chemokine 19 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-C motif chemokine 19 antibodies...
Designing a Western blot for C-C motif chemokine 19? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CCL19 Western Blot GuideDesigning an IHC experiment for C-C motif chemokine 19? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CCL19 IHC GuideCCL19 Infographic by Boster Bio
All CCL19 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0456
96 wells/kit, with removable strips.
Cat # EK0456
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0456
5 plates/kit
Cat # EZ0456
5 plates/kit
Mouse
ELISA
$499
Cat # EK0457
96 wells/kit, with removable strips.
Cat # EK0457
96 wells/kit, with removable strips.
Mouse, Rat
WB
$370
Cat # A01605-1
100 μg/vial
Cat # A01605-1
100 μg/vial
Human
$628
Cat # LS006363
20 µg, 100 µg
Cat # LS006363
20 µg, 100 µg
CCL19 Overview
Facts about C-C motif chemokine 19.
C-C motif chemokine 19 (CCL19)
May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an essential role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs.
Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes.
Gene Information
| Human | |
|---|---|
| Gene Name: | CCL19 |
| Uniprot: | Q99731 |
| Entrez: | 6363 |
Family
| Belongs to: |
|---|
| intercrine beta (chemokine CC) family |
Alternative Names
beta chemokine exodus-3; Beta-chemokine exodus-3; CC chemokine ligand 19; C-C motif chemokine 19; CCL19; chemokine (C-C motif) ligand 19; CKb11; EBI1-ligand chemokine; ELC; ELCMIP-3-beta; Epstein-Barr virus-induced molecule 1 ligand chemokine; exodus-3; Macrophage inflammatory protein 3 beta; macrophage inflammatory protein 3-beta; MGC34433; MIP3 beta; MIP-3 beta; MIP-3b; MIP3BCK beta-11; SCYA19EBI1 ligand chemokine; small inducible cytokine subfamily A (Cys-Cys), member 19; Small-inducible cytokine A19
Molecular Weight
Mass (kDA):
10.993 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p13.3 |
| Sequence: | 9; NC_000009.12 (34689570..34691276, complement) |
Tissue Specificity
Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Cholangiocarcinoma
- Neoplasms
- Malignant Neoplasms
- Tissue Adhesions
- Autoimmune Reaction
- Neoplasm Metastasis
- Autoimmune Diseases
- Carcinoma
- Arthritis
- Nervousness
- Immunologic Deficiency Syndromes
- Leukemia
Interacting Proteins
- TNFAIP6
Pathways
- Chemotaxis
- Cell Migration
- Immune Response
- Secretion
- Pathogenesis
- Cell Proliferation
- Localization
- Cytokine Production
- Cell Adhesion
- Cell Activation
- Dendritic Cell Migration
- Lymphocyte Migration
- T Cell Proliferation
PTMs
- Phosphorylation
- Glycosylation
- Reduction
- Deacetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCL19
bosterbio.com/bosterbio-gene-info-cards/CCL19
References
PMID: 9013939 by Rossi D.L., et al. Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta.
PMID: 9153236 by Yoshida R., et al. Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7.
1 Publications of Boster C-C motif chemokine 19 Antibodies & ELISA Kits
- PubMed ID: 30282817, Gut microbiota%u2013dependent modulation of innate immunity and lymph node remod...
*More publications can be found for each product on its corresponding product page