Dachshund homolog 1 Antibodies

AND DACH1 ELISA kits, Dachshund homolog 1 Proteins

Many biological assays use antibodies to detect Dachshund homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dachshund homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dachshund homolog 1 antibodies...

We validate the specificity of these antibodies to Dachshund homolog 1 by testing them on tissues known to express DACH1 positively and negatively. Browse below to find the DACH1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DACH1 Infographic by Boster Bio

All DACH1 Products

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Anti-Dachshund homolog 1 DACH1 Antibody

Western blot analysis of extracts of various cell lines, using DACH1 antibody at 1:1000 dilution

Mouse, Rat

$405
Cat # A04359
100ul

DACH1 (NM_080759) Human Over-expression Lysate

Human

$960
Cat # LS001602
20 µg, 100 µg

Anti-DACH1 Antibody

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A04359-3
100 μl/vial

DACH1 Overview

Facts about Dachshund homolog 1.

DACH1 3D structure. Source: alphafold

Dachshund homolog 1 (DACH1)

Transcription factor that is involved in regulation of organogenesis. Seems like a regulator of SIX1, SIX6 and likely SIX5.

Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation appears also to involve institution of CREBBP.

Gene Information

Human
Gene Name:	DACH1
Uniprot:	Q9UI36
Entrez:	1602

Family

Belongs to:

DACH/dachshund family

Alternative Names

Dach1; DACHdachshund homolog 1; dachshund homolog (Drosophila); dachshund homolog 1 (Drosophila); FLJ10138

Molecular Weight

Mass (kDA):
78.562 kDA

Genomic Context


Human

Location:	13q21.33
Sequence:	13; NC_000013.11 (71437966..71868068, complement)

Tissue Specificity

Widely expressed. Isoform 2 is found in brain, heart, kidney, liver, leukocytes and spleen. Isoform 3 is found in liver and heart. Isoform 4 is found in spleen.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Neoplasm Metastasis
Mammary Neoplasms
Cell Transformation, Neoplastic
Tissue Adhesions
Hyperplasia
Neoplasm Invasiveness
Carcinoma
Chronic Kidney Disease
Nervousness
Kidney Failure, Chronic

Kidney Diseases
Malignant Neoplasm Of Ovary
Malignant Neoplasm Of Prostate
Leukemia
Branchio-oto-renal Syndrome
Pituitary Diseases
Ovarian Neoplasm

Interacting Proteins

AHCYL1
FGF12
MMTAG2
NAGK
NCOR1

PPIG
RNF14
SMAD4
U2AF2
ZCCHC10

Pathways

Cell Fate Determination
Cell Proliferation
Eye Development
Cell Cycle
Cell Adhesion
Translation
Cell Death
Transport
Brain Development
Oncogenesis
Localization
Glomerular Filtration
Methylation

Pathogenesis
Cell Activation
Oxidative Phosphorylation
Ossification
Limb Development
Nuclear Transport
Reverse Transcription

PTMs

Phosphorylation
Methylation

Acetylation
Dephosphorylation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DACH1

References

PMID: 10502110 by Kozmik Z., et al. Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene.

PMID: 11543628 by Ayres J.A., et al. Dach: genomic characterization, evaluation as a candidate for postaxial polydactyly type A2, and developmental expression pattern of the mouse homolog.