This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
1 Citations
1 Citations
Facts about Drebrin.
.
| Human | |
|---|---|
| Gene Name: | DBN1 |
| Uniprot: | Q16643 |
| Entrez: | 1627 |

| Belongs to: |
|---|
| No superfamily |

D0S117E; DBN1; Developmentally-regulated brain protein; DKFZp434D064; Drba; Drebrin 1; Drebrin A; Drebrin E; Drebrin E2; drebrin; drebrin-1
Mass (kDA):
71.429 kDA

| Human | |
|---|---|
| Location: | 5q35.3 |
| Sequence: | 5; NC_000005.10 (177456592..177480368, complement) |
Cytoplasm. Cell projection, dendrite. Cytoplasm, cell cortex. Cell junction. Cell projection, growth cone. In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm (PubMed:20215400). In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC) (PubMed:20215400). Colocalized with RUFY3 and F-actin at the transitional domain of the axonal growth cone (By similarity).






PMID: 8216329 by Toda M., et al. Molecular cloning of cDNA encoding human drebrin E and chromosomal mapping of its gene.
PMID: 8838578 by Harigaya Y., et al. Disappearance of actin-binding protein, drebrin, from hippocampal synapses in Alzheimer's disease.
*More publications can be found for each product on its corresponding product page