This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Drebrin Antibodies
AND DBN1 ELISA kits, Drebrin Proteins
Many biological assays use antibodies to detect Drebrin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Drebrin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Drebrin antibodies...
Designing a Western blot for Drebrin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DBN1 Western Blot GuideDBN1 Infographic by Boster Bio
All DBN1 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M05530-4
100 μg/vial
Cat # M05530-4
100 μg/vial
Anti-Drebrin/DBN1 Antibody Picoband®
1 Citations
Human, Monkey, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05530-1
100 μg/vial
Cat # A05530-1
100 μg/vial
Anti-Drebrin DBN1 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IP, IF, ICC, WB
$370
Cat # M05530
100 μl
Cat # M05530
100 μl
Human, Mouse, Rat
IHC, WB
$523
Cat # M05530-3
100 µl
Cat # M05530-3
100 µl
DBN1 Overview
Facts about Drebrin.
Drebrin (DBN1)
Drebrins may play some role in cell migration, extension of neuronal processes and plasticity of dendrites. Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruiting to IS.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | DBN1 |
| Uniprot: | Q16643 |
| Entrez: | 1627 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
D0S117E; DBN1; Developmentally-regulated brain protein; DKFZp434D064; Drba; Drebrin 1; Drebrin A; Drebrin E; Drebrin E2; drebrin; drebrin-1
Molecular Weight
Mass (kDA):
71.429 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q35.3 |
| Sequence: | 5; NC_000005.10 (177456592..177480368, complement) |
Subcellular Localizations
Cytoplasm. Cell projection, dendrite. Cytoplasm, cell cortex. Cell junction. Cell projection, growth cone. In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm (PubMed:20215400). In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC) (PubMed:20215400). Colocalized with RUFY3 and F-actin at the transitional domain of the axonal growth cone (By similarity).
Diseases
- Lung Injury
- Cell Transformation, Neoplastic
- Lung Neoplasms
- Respiratory Distress Syndrome, Newborn
- Non-small Cell Lung Carcinoma
- Tissue Adhesions
- Malignant Neoplasm Of Lung
- Respiratory Distress
- Fibrosis
Interacting Proteins
- AFDN
- Afdn
- CXCR4
- GRB2
- GRN
- PTEN
- TINF2
- ZMYND8
Pathways
- Neurogenesis
- Cell Adhesion
- Actin Cytoskeleton Organization
- Cytoskeleton Organization
- Cell Proliferation
- Translation
- Tissue Remodeling
- Lung Development
PTMs
- Acetylation
Research Areas
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DBN1
bosterbio.com/bosterbio-gene-info-cards/DBN1
References
PMID: 8216329 by Toda M., et al. Molecular cloning of cDNA encoding human drebrin E and chromosomal mapping of its gene.
PMID: 8838578 by Harigaya Y., et al. Disappearance of actin-binding protein, drebrin, from hippocampal synapses in Alzheimer's disease.
1 Publications of Boster Drebrin Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.tox.2017.04.001, The induction of cytochrome P450 2E1 by ethanol leads to the loss of synaptic pr...
*More publications can be found for each product on its corresponding product page