DEDD Antibodies

AND DEDD ELISA kits, DEDD Proteins

Many biological assays use antibodies to detect DEDD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DEDD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DEDD antibodies...

We validate the specificity of these antibodies to DEDD by testing them on tissues known to express DEDD positively and negatively. Browse below to find the DEDD antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DEDD Infographic by Boster Bio

All DEDD Products

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Product

Figures

Specificity

Applications

Price

Anti-DEDD Antibody

Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night

Human, Mouse, Rat

ELISA, WB

$380
Cat # A06463
100ul

Human DEDD Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$265
Cat # PROTO75618
Starting from 10ug

Anti-DEDD Mouse Monoclonal Antibody [Clone ID: OTI7C9]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DEDD (Right lane) cDNA for 48 hrs and lysed

Human, Mouse, Rat

$523
Cat # M06463
100 µl

DEDD (NM_032998) Human Over-expression Lysate

DEDD Human Over-expression Lysates NM_001039711

Human

$628
Cat # LS009191
20 µg, 100 µg

DEDD Overview

Facts about Death effector domain-containing protein.

DEDD 3D structure. Source: alphafold

Death effector domain-containing protein (DEDD)

A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18.

Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the action of GTF3C3.

Gene Information

Human
Gene Name:	DEDD
Uniprot:	O75618
Entrez:	9191

Family

Belongs to:

No superfamily

Alternative Names

CASP8IP1; death effector domain containing; death effector domain-containing protein; Death effector domain-containing testicular molecule; death effector domain-containing; DEDD1; DEDPRO1; DEFTKE05; FLDED1; FLDED-1

Molecular Weight

Mass (kDA):
36.794 kDA

Genomic Context


Human

Location:	1q23.3
Sequence:	1; NC_000001.11 (161120974..161132783, complement)

Tissue Specificity

Widely expressed with highest levels in testis.

Subcellular Localizations

Cytoplasm. Nucleus, nucleolus. Translocated to the nucleus during CD95-mediated apoptosis where it is localized in the nucleoli (By similarity). Following apoptosis induction, the mono and/or diubiquitination form increases and forms filamentous structures that colocalize with KRT8 and KRT18 intermediate filament network in simple epithelial cells.