DNAH5 Antibodies

AND DNAH5 ELISA kits, DNAH5 Proteins

Many biological assays use antibodies to detect DNAH5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNAH5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNAH5 antibodies...

We validate the specificity of these antibodies to DNAH5 by testing them on tissues known to express DNAH5 positively and negatively. Browse below to find the DNAH5 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DNAH5 Infographic by Boster Bio

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DNAH5 Overview

Facts about Dynein heavy chain 5, axonemal.

Dynein heavy chain 5, axonemal (DNAH5)

Force generating protein of respiratory cilia. Produces force to the minus ends of microtubules.

Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles.

Gene Information

Human
Gene Name:	DNAH5
Uniprot:	Q8TE73
Entrez:	1767

Family

Belongs to:

dynein heavy chain family

Alternative Names

Axonemal beta dynein heavy chain 5; CILD3KIAA1603; Ciliary dynein heavy chain 5; dynein heavy chain 5, axonemal; dynein, axonemal, heavy chain 5; dynein, axonemal, heavy polypeptide 5; FLJ46759; HL1DNAHC5; KTGNR; PCDDnahc5

Molecular Weight

Mass (kDA):
529.021 kDA

Genomic Context


Human

Location:	5p15.2
Sequence:	5; NC_000005.10 (13690328..14011829, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton, cilium axoneme.

Diseases

Dyskinetic Syndrome
Ciliary Motility Disorders
Kartagener Syndrome
Situs Inversus
Infective Disorder
Infertility
Hereditary Diseases
Male Infertility
Superior Oblique Overaction
Retinitis Pigmentosa
Situs Ambiguus
Respiratory Tract Infections

Heart Diseases
Bronchiectasis
Hydrocephalus
Respiratory Distress
Congenital Heart Disease
Limb Deformities, Congenital
Polyps

Pathways

Pathogenesis
Transport
Sperm Motility
Localization
Cell Proliferation
Brain Development
Chromatin Organization

Intraflagellar Transport

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DNAH5

References

PMID: 11788826 by Olbrich H., et al. Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry.

PMID: 11062149 by Omran H., et al. Homozygosity mapping of a gene locus for primary ciliary dyskinesia on chromosome 5p and identification of the heavy dynein chain DNAH5 as a candidate gene.