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Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery period length of the heat shock response (PubMed:9499401). Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).
|Sequence:||19; NC_000019.10 (14514764..14530597, complement)|
Cytoplasm. Nucleus. Nucleus, nucleolus. Translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock.