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In arrested oocytes, plays a role in meiotic resumption (By similarity). Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complicated in oocytes, likely by dephosphorylating and inactivating the conventional protein kinase C (cPKC) isozyme PRKCB (By similarity).
|protein-tyrosine phosphatase family|
|Sequence:||3; NC_000003.12 (52048919..52056571, complement)|
Strongly expressed in liver (PubMed:8670865). Expressed at significantly higher levels in malignant hematopoietic cells than in corresponding non-malignant cells (PubMed:14576828).