This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
DYNLL1 Antibodies
AND DYNLL1 ELISA kits, DYNLL1 Proteins
Many biological assays use antibodies to detect DYNLL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DYNLL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DYNLL1 antibodies...
Designing a Western blot for DYNLL1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DYNLL1 Western Blot GuideDYNLL1 Infographic by Boster Bio
All DYNLL1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03454-2
100 μg/vial
Cat # A03454-2
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M03454
100 μl
Cat # M03454
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03454-1
100 μg/vial
Cat # M03454-1
100 μg/vial
DYNLL1 Overview
Facts about Dynein light chain 1, cytoplasmic.
Dynein light chain 1, cytoplasmic (DYNLL1)
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. .
Gene Information
| Human | |
|---|---|
| Gene Name: | DYNLL1 |
| Uniprot: | P63167 |
| Entrez: | 8655 |
Family
| Belongs to: |
|---|
| dynein light chain family |
Alternative Names
cytoplasmic dynein light polypeptide; DLC1; DLC1DNCLC1; DLC8; DLC8MGC126137; DNCL1; DNCL1MGC126138; DNCLC1; dynein light chain 1, cytoplasmic; Dynein light chain LC8-type 1; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1,8 kDa dynein light chain; DYNLL1; hdlc1; LC8; LC8a; PIN; PINLC8a; Protein inhibitor of neuronal nitric oxide synthase
Molecular Weight
Mass (kDA):
10.366 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q24.31 |
| Sequence: | 12; NC_000012.12 (120469842..120498493) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Nucleus. Mitochondrion. Upon induction of apoptosis translocates together with BCL2L11 to mitochondria.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Virus Diseases
- Classical Swine Fever
- Neoplasms
- Nervousness
- Infective Disorder
- African Swine Fever
- Malignant Paraganglionic Neoplasm
- Hypertensive Disease
- Autoimmunity
- Stenosis
- Kartagener Syndrome
Interacting Proteins
- CCDC36
- DNAL4
- FAM117B
- GPHN
- IQUB
- KANK2
- MYZAP
- NEK9
- RACK1
- SMCP
Pathways
- Transport
- Localization
- Mitosis
- Protein Folding
- Pathogenesis
- Anaphase
- Cell Division
- Cell Cycle
- Nuclear Import
- Cell Death
- Autophagy
- Mammary Gland Involution
- Programmed Cell Death
PTMs
- Phosphorylation
- Nitration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DYNLL1
bosterbio.com/bosterbio-gene-info-cards/DYNLL1
References
PMID: 8628263 by Dick T., et al. Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster.
PMID: 10198631 by Puthalakath H., et al. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex.