This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial.
Involved in the BMP signaling pathway. Required for normal embryonic development.
| Mouse | |
|---|---|
| Gene Name: | Ecsit |
| Uniprot: | Q9QZH6 |
| Entrez: | 26940 |

| Belongs to: |
|---|
| ECSIT family |

ECSIT homolog (Drosophila); evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; likely ortholog of mouse signaling intermediate in Toll pathway evolutionarilyconserved; Protein SITPEC; signaling intermediate in Toll pathway evolutionarily conserved ortholog; SITPECsignaling intermediate in Toll pathway, evolutionarily conserved
Mass (kDA):
49.799 kDA

| Mouse | |
|---|---|
| Location: | 9|9 A3 |
| Sequence: | 9; |
Detected in heart, brain, lung, liver, skeletal muscle, kidney and testis. Detected in embryonic mesoderm and epiblast, and in extraembryonic ectoderm.




PMID: 10465784 by Kopp E., et al. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway.
PMID: 14633973 by Xiao C., et al. Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.