EIF2B1 Antibodies

AND EIF2B1 ELISA kits, EIF2B1 Proteins

Many biological assays use antibodies to detect EIF2B1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF2B1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF2B1 antibodies...

We validate the specificity of these antibodies to EIF2B1 by testing them on tissues known to express EIF2B1 positively and negatively. Browse below to find the EIF2B1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EIF2B1 Infographic by Boster Bio

All EIF2B1 Products

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Specificity

Applications

Price

Anti-EIF2B1 Antibody

Western blot analysis of extracts of various cell lines, using EIF2B1 antibody at 1:1000 dilution

Immunofluorescence analysis of U2OS cells using EIF2B1 antibody at dilution of 1:100

Human, Mouse

IF, ICC, WB

$405
Cat # A04239
100ul

Anti-EIF2B1 Antibody Picoband®

Western blot analysis of EIF2B1 using anti-EIF2B1 antibody (A04239-1)

IHC analysis of EIF2B1 using anti-EIF2B1 antibody (A04239-1)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04239-1
100 μg/vial

Human EIF2B1 Recombinant Protein

SDS-PAGE

$350
Cat # PROTQ14232
Starting from 10ug

EIF2B1 (NM_001414) Human Over-expression Lysate

Human

$628
Cat # LS001967
20 µg, 100 µg

EIF2B1 Overview

Facts about Translation initiation factor eIF-2B subunit alpha.

EIF2B1 3D structure. Source: alphafold

Translation initiation factor eIF-2B subunit alpha (EIF2B1)

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. .

Gene Information

Human
Gene Name:	EIF2B1
Uniprot:	Q14232
Entrez:	1967

Family

Belongs to:

eIF-2B alpha/beta/delta subunits family

Alternative Names

eIF-2B GDP-GTP exchange factor subunit alpha; EIF2B; EIF-2B; EIF-2Balpha; EIF2BAMGC117409; eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD); eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; MGC125868; MGC125869; translation initiation factor eIF-2B subunit alpha

Molecular Weight

Mass (kDA):
33.712 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (123620406..123633686, complement)

Diseases

Leukoencephalopathies
Ataxia
Leukoencephalopathy With Vanishing White Matter
Optic Atrophy
Muscle Spasticity
Cerebellar Ataxia
Atrophy
Brain Diseases
Amenorrhea
Craniocerebral Trauma
Premature Menopause

Non-neoplastic Disorder
Primary Physiologic Amenorrhea
Carcinoma
Neoplasms
Nervousness

Interacting Proteins

Adra2a
Adra2b
GORASP2
RD3
WDYHV1

Pathways

Translation

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF2B1

References

PMID: 11835386 by van der Knaap M.S., et al. Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter.

PMID: 15776425 by Ohlenbusch A., et al. Identification of ten novel mutations in patients with eIF2B-related disorders.