ENPP4 Antibodies

AND ENPP4 ELISA kits, ENPP4 Proteins

Many biological assays use antibodies to detect ENPP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ENPP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ENPP4 antibodies...

We validate the specificity of these antibodies to ENPP4 by testing them on tissues known to express ENPP4 positively and negatively. Browse below to find the ENPP4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ENPP4 Infographic by Boster Bio

All ENPP4 Products

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Anti-ENPP4 Antibody Picoband®

Western blot analysis of ENPP4 using anti-ENPP4 antibody (A11668)

IHC analysis of ENPP4 using anti-ENPP4 antibody (A11668)

Flow Cytometry analysis of 293T cells using anti-ENPP4 antibody (A11668)

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A11668
100 μg/vial

ENPP4 Overview

Facts about Bis(5'-adenosyl)-triphosphatase ENPP4.

ENPP4 3D structure. Source: alphafold

Bis(5'-adenosyl)-triphosphatase ENPP4 (ENPP4)

Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP.
Ap3A and Ap4A are diadenosine polyphosphates believed to induce proliferation of vascular smooth muscle cells.

Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors. .

Gene Information

Human
Gene Name:	ENPP4
Uniprot:	Q9Y6X5
Entrez:	22875

Family

Belongs to:

nucleotide pyrophosphatase/phosphodiesterase family

Alternative Names

AP3Aase; EC 3.1; ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative); E-NPP 4; ENPP4; ENPP-4; KIAA0879ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function); NPP-4; NPP4ectonucleotide pyrophosphatase/phosphodiesterase family member 4

Molecular Weight

Mass (kDA):
51.641 kDA

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (46129989..46146688)

Tissue Specificity

Expressed on the surface of vascular endothelia.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Neoplasm Metastasis
Delayed Graft Function
Lung Neoplasms
Ischemia
Primary Neoplasm
Metastatic Malignant Neoplasm To The Lung
Tumor Progression
Inflammatory Response
Osteosarcoma

Malignant Neoplasms
Neoplasms
Cold Ischemia

Pathways

Bioluminescence
Immune Response
Inflammatory Response

PTMs

Disulfide bond

Glycoprotein

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ENPP4

References

PMID: 11027689 by Gijsbers R., et al. Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases.

PMID: 22995898 by Albright R.A., et al. NPP4 is a procoagulant enzyme on the surface of vascular endothelium.