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- Table of Contents
Facts about FAS-associated factor 1.
Potentiates but can't initiate FAS-induced apoptosis (By similarity). .
Human | |
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Gene Name: | FAF1 |
Uniprot: | Q9UNN5 |
Entrez: | 11124 |
Belongs to: |
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No superfamily |
CGI-03; Fas (TNFRSF6) associated factor 1; HFAF1s; TNFRSF6-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A; UBXD12FLJ37524; UBXN3AhFAF1FAS-associated factor 1
Mass (kDA):
73.954 kDA
Human | |
---|---|
Location: | 1p32.3 |
Sequence: | 1; NC_000001.11 (50437028..50960267, complement) |
Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes.
Nucleus.
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PMID: 10462485 by Ryu S.-W., et al. Identification and characterization of human Fas associated factor 1, hFAF1.
PMID: 21978668 by Pinheiro A.S., et al. The NLRP12 pyrin domain: structure, dynamics, and functional insights.