FAS-associated factor 1 Antibodies

AND FAF1 ELISA kits, FAS-associated factor 1 Proteins

Many biological assays use antibodies to detect FAS-associated factor 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FAS-associated factor 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FAS-associated factor 1 antibodies...

We validate the specificity of these antibodies to FAS-associated factor 1 by testing them on tissues known to express FAF1 positively and negatively. Browse below to find the FAF1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for FAS-associated factor 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the FAF1 Western Blot Guide

FAF1 Infographic by Boster Bio

All FAF1 Products

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Product

Figures

Specificity

Applications

Price

Anti-FAF1 Antibody Picoband®

Western blot analysis of FAF1 using anti-FAF1 antibody (A03842-1)

IF analysis of FAF1 using anti-FAF1 antibody (A03842-1) and anti-Beta Tubulin antibody (M01857-3)

Flow Cytometry analysis of K562 cells using anti-FAF1 antibody (A03842-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03842-1
100 μg/vial

Anti-FAS-associated factor 1 FAF1 Antibody

Western blot analysis of FAF1 in THP-1 cell lysate with FAF1 antibody at (A) 1 and (B) 2 μg/mL

Immunohistochemistry of FAF1 in rat spleen tissue with FAF1 antibody at 2

Immunofluorescence of FAF1 in rat spleen tissue with FAF1 antibody at 2 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A03842
0.1 mg

FAF1 (NM_007051) Human Over-expression Lysate

Human

$628
Cat # LS011124
20 µg, 100 µg

FAF1 (NM_007051) Human Recombinant Protein

Coomassie blue staining of purified FAF1 protein

$1062
Cat # PROTQ9UNN5
20 µg

FAF1 Overview

Facts about FAS-associated factor 1.

FAF1 3D structure. Source: alphafold

FAS-associated factor 1 (FAF1)

Ubiquitin-binding protein (PubMed:19722279). Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (PubMed:26842564).

Potentiates but can't initiate FAS-induced apoptosis (By similarity). .

Gene Information

Human
Gene Name:	FAF1
Uniprot:	Q9UNN5
Entrez:	11124

Family

Belongs to:

No superfamily

Alternative Names

CGI-03; Fas (TNFRSF6) associated factor 1; HFAF1s; TNFRSF6-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A; UBXD12FLJ37524; UBXN3AhFAF1FAS-associated factor 1

Molecular Weight

Mass (kDA):
73.954 kDA

Genomic Context


Human

Location:	1p32.3
Sequence:	1; NC_000001.11 (50437028..50960267, complement)

Tissue Specificity

Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Malignant Neoplasms
Leukemia
Carcinoma
Mesothelioma
Myeloid Leukemia
Inflammation
Uniparental Disomy
Aortic Aneurysm, Abdominal
Leukemia, T-cell
Parkinson Disease
Leukemia, Myelocytic, Acute
Adult T-cell Lymphoma/leukemia

Cell Transformation, Neoplastic
Autoimmune Reaction
Stomach Neoplasms
Jaw Abnormalities
Non-neoplastic Disorder
Malignant Neoplasm Of Breast
Malignant Tumor Of Colon

Interacting Proteins

Pathways

Cell Death
Pathogenesis
Cell Cycle
Oncogenesis
Localization
Rna Interference
Transport
Cell Adhesion
Cell Activation
Cell Migration
Osteoblast Differentiation
Proteolysis
Immune Response

Translation
Axon Guidance
Innate Immune Response
Cell Differentiation
Mitochondrial Translational Initiation
Nuclear Import
Translational Initiation

PTMs

Ubiquitination
Phosphorylation

Cleavage
Oxidation

Research Areas

Apoptosis
Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FAF1

References

PMID: 10462485 by Ryu S.-W., et al. Identification and characterization of human Fas associated factor 1, hFAF1.

PMID: 21978668 by Pinheiro A.S., et al. The NLRP12 pyrin domain: structure, dynamics, and functional insights.