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- Table of Contents
Facts about High affinity immunoglobulin epsilon receptor subunit alpha.
Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE contributes to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy.
| Human | |
|---|---|
| Gene Name: | FCER1A |
| Uniprot: | P12319 |
| Entrez: | 2205 |

| Belongs to: |
|---|
| No superfamily |

Fc epsilon RI alpha; FCE1A; FCER1A; FcERI; FceRIa
Mass (kDA):
29.596 kDA

| Human | |
|---|---|
| Location: | 1q23.2 |
| Sequence: | 1; NC_000001.11 (159283888..159308224) |
Cell membrane; Single-pass type I membrane protein.


PMID: 2967464 by Kochan J., et al. Isolation of the gene coding for the alpha subunit of the human high affinity IgE receptor.
PMID: 2964640 by Shimizu A., et al. Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products.