Leucine-rich repeat transmembrane protein FLRT3 (FLRT3)

Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role based on its interaction partners. Plays a role in cerebral development in the retina (By similarity).

Plays a role in cell-cell adhesion through its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:26235030). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards tissues expressing NTN1.