FMO2 Antibodies

AND FMO2 ELISA kits, FMO2 Proteins

Many biological assays use antibodies to detect FMO2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FMO2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FMO2 antibodies...

We validate the specificity of these antibodies to FMO2 by testing them on tissues known to express FMO2 positively and negatively. Browse below to find the FMO2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FMO2 Infographic by Boster Bio

All FMO2 Products

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Specificity

Applications

Price

Anti-FMO2 Antibody Picoband®

7 Q&As

Western blot analysis of FMO2 using anti-FMO2 antibody (PB9760)

Human, Mouse, Rat

$370
Cat # PB9760
100 μg/vial

FMO2 (NM_001460) Human Recombinant Protein

Coomassie blue staining of purified FMO2 protein

$1062
Cat # PROTQ99518
20 µg

FMO2 (NM_001460) Human Over-expression Lysate

Human

$628
Cat # LS002327
20 µg, 100 µg

FMO2 Overview

Facts about Dimethylaniline monooxygenase [N-oxide-forming] 2.

FMO2 3D structure. Source: alphafold

Dimethylaniline monooxygenase [N-oxide-forming] 2 (FMO2)

Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine.

Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive.

Gene Information

Human
Gene Name:	FMO2
Uniprot:	Q99518
Entrez:	2327

Family

Belongs to:

FMO family

Alternative Names

dimethylaniline monooxygenase [N-oxide-forming] 2; Dimethylaniline oxidase 2; EC 1.14.13.8; flavin containing monooxygenase 2 (non-functional); flavin containing monooxygenase 2; FLJ40826; FMO 1B1; FMO 2; FMO, pulmonary; FMO1B1; Pulmonary flavin-containing monooxygenase 2

Molecular Weight

Mass (kDA):
60.907 kDA

Genomic Context


Human

Location:	1q24.3
Sequence:	1; NC_000001.11 (171185208..171212686)

Tissue Specificity

Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain.

Subcellular Localizations

Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.

Diseases

Trimethylaminuria
Carcinoma
Malignant Neoplasms
Neoplasms
Intolerant Of Heat
Tuberculosis
Inborn Errors Of Metabolism
Malignant Neoplasm Of Breast
Liver Damage
Cytosine To Thymidine Transition Abnormality
Neoplasm Invasiveness
Macular Corneal Dystrophy Type I

Hypokinesia
Nonalcoholic Steatohepatitis
Invasive Ductal Breast Carcinoma
Mouth Neoplasms
Feline Urological Syndrome
Nervousness
Invasive Lobular Breast Carcinoma

Pathways

Localization
Nadph Oxidation
Pathogenesis
Transport
Methylation
Reverse Transcription
Response To Ionizing Radiation
Dna Amplification
Parturition

Response To Ph
Metaphase
Oncogenesis

PTMs

Oxidation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FMO2

References

PMID: 9804831 by Dolphin C.T., et al. The flavin-containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, nonfunctional protein.

PMID: 11042094 by Whetstine J.R., et al. Ethnic differences in human flavin-containing monooxygenase 2 (FMO2) polymorphisms: detection of expressed protein in African-Americans.