FNDC5 Antibodies

AND FNDC5 ELISA kits, FNDC5 Proteins

Many biological assays use antibodies to detect FNDC5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FNDC5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FNDC5 antibodies...

We validate the specificity of these antibodies to FNDC5 by testing them on tissues known to express FNDC5 positively and negatively. Browse below to find the FNDC5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for FNDC5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the FNDC5 Western Blot Guide

FNDC5 Infographic by Boster Bio

All FNDC5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-FNDC5 Antibody Picoband®

Western blot analysis of FNDC5 using anti-FNDC5 antibody (A02538-1)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A02538-1
100 μg/vial

Anti-FNDC5 Antibody

Human

$299
Cat # M02538
50 µl

FNDC5 (NM_153756) Human Over-expression Lysate

Human

$628
Cat # LS252995
20 µg, 100 µg

Anti-FNDC5 Rabbit Monoclonal Antibody

1 Citations

Western blot analysis of FNDC5 expression in Rat muscle cell lysate

Human, Mouse, Rat

$370
Cat # M02538-1
100 μl/vial

FNDC5 Overview

Facts about Fibronectin type III domain-containing protein 5.

FNDC5 3D structure. Source: alphafold

Fibronectin type III domain-containing protein 5 (FNDC5)

Irisin: Unlike mouse, might not be involved in the beneficial effects of muscular exercise, nor at the induction of browning of human white adipose tissue. .

Gene Information

Human
Gene Name:	FNDC5
Uniprot:	Q8NAU1
Entrez:	252995

Family

Belongs to:

No superfamily

Alternative Names

fibronectin type III domain containing 5; fibronectin type III domain-containing protein 5; FNDC5; FRCP2; FRCP2Fibronectin type III repeat-containing protein 2; Irisin

Molecular Weight

Mass (kDA):
23.659 kDA

Genomic Context


Human

Location:	1p35.1
Sequence:	1; NC_000001.11 (32862268..32872484, complement)

Tissue Specificity

Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Peroxisome membrane; Single-pass type I membrane protein. Imported in peroxisomes through the PEX5 receptor pathway.; [Irisin]: Secreted. Detected in the blood of individuals subjected to endurance exercise.

Diseases

Obesity
Insulin Resistance
Metabolic Diseases
Heart Failure

Pathways

Glucose Homeostasis
Glycolysis

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FNDC5

References

PMID: 22237023 by Bostrom P., et al. A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.

PMID: 24040023 by Raschke S., et al. Evidence against a Beneficial Effect of Irisin in Humans.

1 Publications of Boster FNDC5 Antibodies & ELISA Kits

PubMed ID: 34023283, Li Y,Tang Y,Li Z,Hou G,Du X.CircSOS2 promotes cervical squamous cell carcinoma b...

*More publications can be found for each product on its corresponding product page