FUT3 Antibodies

AND FUT3 ELISA kits, FUT3 Proteins

Many biological assays use antibodies to detect FUT3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FUT3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FUT3 antibodies...

We validate the specificity of these antibodies to FUT3 by testing them on tissues known to express FUT3 positively and negatively. Browse below to find the FUT3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FUT3 Infographic by Boster Bio

All FUT3 Products

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Specificity

Applications

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Anti-FucT-III FUT3 Antibody

Western blot (WB) analysis of FucT-III polyclonal antibody at 1:500 dilution
Lane1:MCF-7 cell lysate
Lane2:Raw264

Human, Mouse, Rat

IHC, ICC, WB

$405
Cat # A03774-1
100ul

Human Fucosyltransferase 3/FUT3 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTP21217
Starting from 10ug

FUT3 (NM_001097639) Human Over-expression Lysate

FUT3 Human Over-expression Lysates NM_001097639

Human

$628
Cat # LS002525
20 µg, 100 µg

FUT3 Overview

Facts about Galactoside 3(4)-L-fucosyltransferase.

FUT3 3D structure. Source: alphafold

Galactoside 3(4)-L-fucosyltransferase (FUT3)

May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. Might be involved in blood group Lewis determination; Lewis-positive (Le(+)) people have an active enzyme while Lewis-negative (Le(-)) people have an inactive enzyme.

Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links. .

Gene Information

Human
Gene Name:	FUT3
Uniprot:	P21217
Entrez:	2525

Family

Belongs to:

glycosyltransferase 10 family

Alternative Names

CD174; FT3B; Fucosyltransferase 3; FucT-III; FUT3; Les; Lewis FT

Molecular Weight

Mass (kDA):
42.117 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (5842888..5851449, complement)

Tissue Specificity

Highly expressed in stomach, colon, small intestine, lung and kidney and to a lesser extent in salivary gland, bladder, uterus and liver.

Subcellular Localizations

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Membrane-bound form in trans cisternae of Golgi.

Diseases

Malignant Neoplasms
Neoplasms
Tissue Adhesions
Carcinoma
Lupus Erythematosus, Systemic
Stomach Neoplasms
Neoplasm Metastasis
Inflammation
Colonic Neoplasms
Malignant Neoplasm Of Stomach
Malignant Tumor Of Colon
Fibrosis
Adenocarcinoma

Malignant Paraganglionic Neoplasm
Cystic Fibrosis
Extravasation
Pancreatic Neoplasm
Infective Disorder
Lung Neoplasms
Atherosclerosis

Pathways

Fucosylation
Cell Adhesion
Glycosylation
Secretion
Sulfation
Methylation
Translation
Pathogenesis
Epithelial Cell-cell Adhesion
Cell Proliferation
Dna Methylation
Virulence

Protein Deacetylation
Dna Replication
Cell Differentiation
Cell Growth
Angiogenesis
Epithelial Cell Differentiation
Cell-cell Adhesion

PTMs

Glycosylation
Cleavage

Methylation
Phosphorylation

Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FUT3

References

PMID: 1977660 by Kukowska-Latallo J.F., et al. A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase.

PMID: 7650030 by Cameron H.S., et al. Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms.