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- Table of Contents
Facts about Transcriptional repressor p66-alpha.
Efficient repression requires the existence of GATAD2B. .
Human | |
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Gene Name: | GATAD2A |
Uniprot: | Q86YP4 |
Entrez: | 54815 |
Belongs to: |
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No superfamily |
FLJ20085; FLJ21017; GATA zinc finger domain containing 2A; GATA zinc finger domain-containing protein 2A; hp66alpha; p66 alpha; p66alpha; transcriptional repressor p66-alpha
Mass (kDA):
68.063 kDA
Human | |
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Location: | 19p13.11 |
Sequence: | 19; NC_000019.10 (19385803..19508932) |
Ubiquitous, both in fetal and adult tissues.
Nucleus speckle. Speckled nuclear localization requires both CR1 and CR2 regions.
PMID: 12183469 by Brackertz M., et al. Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3.
PMID: 16415179 by Brackertz M., et al. p66alpha and p66beta of the Mi-2/NuRD complex mediate MBD2 and histone interaction.