GBA2 Antibodies

AND GBA2 ELISA kits, GBA2 Proteins

Many biological assays use antibodies to detect GBA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GBA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GBA2 antibodies...

We validate the specificity of these antibodies to GBA2 by testing them on tissues known to express GBA2 positively and negatively. Browse below to find the GBA2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GBA2 Infographic by Boster Bio

All GBA2 Products

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GBA2 (NM_020944) Human Over-expression Lysate

Human

$628
Cat # LS057704
20 µg, 100 µg

Anti-GBA2 Antibody Picoband®

Western blot analysis of GBA2 using anti-GBA2 antibody (A08047-1)

Flow Cytometry analysis of A549 cells using anti-GBA2 antibody (A08047-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A08047-1
100 μg/vial

GBA2 Overview

Facts about Non-lysosomal glucosylceramidase.

GBA2 3D structure. Source: alphafold

Non-lysosomal glucosylceramidase (GBA2)

Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation.

May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such action is unclear in vivo. Plays a role in central nevous system development.

Gene Information

Human
Gene Name:	GBA2
Uniprot:	Q9HCG7
Entrez:	57704

Family

Belongs to:

non-lysosomal glucosylceramidase family

Alternative Names

AD035; Beta-glucocerebrosidase 2; Beta-glucosidase 2; bile acid beta-glucosidase; DKFZp762K054; glucosidase, beta (bile acid) 2; Glucosylceramidase 2; KIAA1605EC 3.2.1.45; MGC16895; NLGase; non-lysosomal glucosylceramidase

Molecular Weight

Mass (kDA):
104.649 kDA

Genomic Context


Human

Location:	9p13.3
Sequence:	9; NC_000009.12 (35736862..35749228, complement)

Tissue Specificity

Widely expressed. Highly expressed in brain, heart, skeletal muscle, kidney and placenta and expressed at lower level in liver.

Subcellular Localizations

Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Localization to the plasma membrane and alternative topologies have also been reported.