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May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such action is unclear in vivo. Plays a role in central nevous system development.
|non-lysosomal glucosylceramidase family|
|Sequence:||9; NC_000009.12 (35736862..35749228, complement)|
Widely expressed. Highly expressed in brain, heart, skeletal muscle, kidney and placenta and expressed at lower level in liver.
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Localization to the plasma membrane and alternative topologies have also been reported.