- Table of Content
Cleaves HJs by a nick and counter-nick mechanism involving double coordinated incisions that lead to the formation of ligatable nicked duplex solutions. Cleavage of the first strand is rate limiting, while second strand cleavage is rapid.
|XPG/RAD2 endonuclease family|
Expressed in bone marrow and testis and to a lesser extent in thymus, spleen, brain and colon.