GFM2 Antibodies

AND GFM2 ELISA kits, GFM2 Proteins

Many biological assays use antibodies to detect GFM2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GFM2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GFM2 antibodies...

We validate the specificity of these antibodies to GFM2 by testing them on tissues known to express GFM2 positively and negatively. Browse below to find the GFM2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GFM2 Infographic by Boster Bio

All GFM2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-EF-G2 GFM2 Antibody

Western blot analysis of lysates from LOVO and RAW264

Immunofluorescence analysis of A549 cells, using GFM2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A11675-1
100ul

GFM2 (NM_032380) Human Recombinant Protein

Coomassie blue staining of purified GFM2 protein

$1249
Cat # PROTQ969S9
20 µg

GFM2 (NM_032380) Human Over-expression Lysate

GFM2 Human Over-expression Lysates NM_032380

Human

$628
Cat # LS084340
20 µg, 100 µg

GFM2 Overview

Facts about Ribosome-releasing factor 2, mitochondrial.

GFM2 3D structure. Source: alphafold

Ribosome-releasing factor 2, mitochondrial (GFM2)

Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in cooperation with MRRF.

GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.

Gene Information

Human
Gene Name:	GFM2
Uniprot:	Q969S9
Entrez:	84340

Family

Belongs to:

TRAFAC class translation factor GTPase superfamily

Alternative Names

EFG2MSTP027; Elongation factor G 2, mitochondrial; Elongation factor G2; G elongation factor, mitochondrial 2; mitochondrial; MRRF2; MST027

Molecular Weight

Mass (kDA):
86.601 kDA

Genomic Context


Human

Location:	5q13.3
Sequence:	5; NC_000005.10 (74721206..74767371, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Mitochondrion.

Diseases

Microcephaly
Diabetes Mellitus, Insulin-dependent
Familial Aplasia Of The Vermis
Diabetes Mellitus

Interacting Proteins

BANP
TRIM27
TRIM9
VPS52

Pathways

Translation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GFM2

References

PMID: 11735030 by Hammarsund M., et al. Identification and characterization of two novel human mitochondrial elongation factor genes, hEFG2 and hEFG1, phylogenetically conserved through evolution.

PMID: 19716793 by Tsuboi M., et al. EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis.