GP1BA Antibodies

AND GP1BA ELISA kits, GP1BA Proteins

Many biological assays use antibodies to detect GP1BA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GP1BA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GP1BA antibodies...

We validate the specificity of these antibodies to GP1BA by testing them on tissues known to express GP1BA positively and negatively. Browse below to find the GP1BA antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for GP1BA? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the GP1BA IHC Guide

GP1BA Infographic by Boster Bio

All GP1BA Products

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Product

Figures

Specificity

Applications

Price

Human CD42b ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2210
96 wells/kit, with removable strips.

Anti-CD42b/GP1BA Antibody

IHC analysis of CD42b/GP1BA using anti-CD42b/GP1BA antibody (A02073-4)

Human, Mouse

ELISA, IHC, WB

$370
Cat # A02073-4
100 μl/vial

CD42b (GP1BA) (NM_000173) Human Over-expression Lysate

Human

$960
Cat # LS002811
20 µg, 100 µg

Anti-CD42b Rabbit Monoclonal Antibody

Human

IHC, WB

$370
Cat # M02073-2
100 μl/vial

GP1BA Overview

Facts about Platelet glycoprotein Ib alpha chain.

GP1BA 3D structure. Source: alphafold

Platelet glycoprotein Ib alpha chain (GP1BA)

GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. .

Gene Information

Human
Gene Name:	GP1BA
Uniprot:	P07359
Entrez:	2811

Family

Belongs to:

No superfamily

Alternative Names

Antigen CD42b-alpha; BP1BA; BSS; CD42b antigen; CD42b; CD42b-alpha; glycoprotein Ib (platelet), alpha polypeptide; Glycoprotein Ibalpha; GP1B; GP1BA; GPIb alpha; GP-Ib alpha; GPIbA; GPIb-alpha; MGC34595; platelet glycoprotein Ib alpha chain; platelet membrane glycoprotein 1b-alpha subunit

Molecular Weight

Mass (kDA):
71.54 kDA

Genomic Context


Human

Location:	17p13.2
Sequence:	17; NC_000017.11 (4932277..4935023)

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Hemorrhage
Von Willebrand Disease
Bleeding Tendency
5,10-methylenetetrahydrofolate Reductase Deficiency
Infarction
Platelet Type Von Willebrand's Disease
Coronary Heart Disease
Heart Diseases
Von Willebrand Disease, Type 2b
Myocardial Infarction
Hypertensive Disease
Diabetes Mellitus
Bernard-soulier Syndrome

Variable Number Tandem Repeat
Cerebrovascular Accident
Tissue Adhesions
Hyperlipidemia
Dysequilibrium Syndrome
Von Willebrand Disease, Type 2
Alloimmunization

Interacting Proteins

GP1BB
GP9
VWF

Pathways

Platelet Aggregation
Coagulation
Hemostasis
Aging
Metaphase
Pathogenesis

Localization

PTMs

Phosphorylation

Research Areas

Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GP1BA

References

PMID: 3303030 by Lopez J.A., et al. Cloning of the alpha chain of human platelet glycoprotein Ib: a transmembrane protein with homology to leucine-rich alpha 2- glycoprotein.

PMID: 2845978 by Wenger R.H., et al. Structure of the human blood platelet membrane glycoprotein Ib alpha gene.