Granzyme H (GZMH)

Cytotoxic chymotrypsin-like serine protease with preference for aromatic and bulky residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses.

Participates in the antiviral response via direct cleavage of several proteins necessary for viral replication. .