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- Table of Contents
GCLM Antibodies
AND GCLM ELISA kits, GCLM Proteins
Many biological assays use antibodies to detect GCLM, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GCLM in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GCLM antibodies...
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GCLM Infographic by Boster Bio
All GCLM Products
Product
Figures
Specificity
Applications
Price
Anti-GCLM Monoclonal Antibody
2 Citations 3 Q&As
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02948
100 μl
Cat # M02948
100 μl
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M02948-2
100 μl/vial
Cat # M02948-2
100 μl/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M02948-3
20μL, 40μL, 100μL, 200μL
Cat # M02948-3
20μL, 40μL, 100μL, 200μL
GCLM Overview
Facts about Glutamate--cysteine ligase regulatory subunit.
Glutamate--cysteine ligase regulatory subunit (GCLM)
Gene Information
| Human | |
|---|---|
| Gene Name: | GCLM |
| Uniprot: | P48507 |
| Entrez: | 2730 |
Family
| Belongs to: |
|---|
| aldo/keto reductase family |
Alternative Names
Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; GCS light chain; GLCLRglutamate--cysteine ligase regulatory subunit; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory(30.8kD); Glutamate--cysteine ligase modifier subunit; glutamate-cysteine ligase regulatory protein; glutamate-cysteine ligase, modifier subunit; GSC light chain
Molecular Weight
Mass (kDA):
30.727 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p22.1 |
| Sequence: | 1; NC_000001.11 (93885199..93910370, complement) |
Tissue Specificity
In all tissues examined. Highest levels in skeletal muscle.
Diseases
- Liver Carcinoma
- Malignant Neoplasms
- Schizophrenia
- Inflammation
- Liver Neoplasms
- Neoplasms
- Myocardial Infarction
- Neurotoxicity Syndromes
- Hepatotoxicity
- Mental Disorders
- Infarction
- Lung Diseases
- Neurodegenerative Disorders
Pathways
- Cell Death
- Pathogenesis
- Cell Proliferation
- Cell Cycle
- Conjugation
- Localization
- Aging
- Cell Growth
- Response To Oxidative Stress
- Inflammatory Response
- Sensitization
- Prepulse Inhibition
- Proestrus
PTMs
- Phosphorylation
- Reduction
- Cleavage
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GCLM
bosterbio.com/bosterbio-gene-info-cards/GCLM
References
PMID: 7826375 by Gipp J.J., et al. Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues.