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- Table of Contents
HHEX Antibodies
AND HHEX ELISA kits, HHEX Proteins
Many biological assays use antibodies to detect HHEX, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HHEX in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HHEX antibodies...
Designing a Western blot for HHEX? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HHEX Western Blot GuideHHEX Infographic by Boster Bio
All HHEX Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, WB
$523
Cat # M02723-1
100 µl
Cat # M02723-1
100 µl
HHEX Overview
Facts about Hematopoietically-expressed homeobox protein HHEX.
Hematopoietically-expressed homeobox protein HHEX (HHEX)
Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor.
May play a role in hematopoietic differentiation. Establishes anterior identification at two levels; acts early to boost canonical WNT-signaling by repressing expression of TLE4, and behaves later to inhibit NODAL-signaling by directly targeting NODAL (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | HHEX |
| Uniprot: | Q03014 |
| Entrez: | 3087 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
hematopoietically expressed homeobox; Hex; HEXHMPH; HHEX; HMPH; Homeobox protein HEX; Homeobox protein PRH; HOX11L-PEN; PRH; PRHhematopoietically-expressed homeobox protein HHEX; PRHX; PRHXhomeobox, hematopoietically expressed; proline-rich homeodomain-containing transcription factor
Molecular Weight
Mass (kDA):
30.022 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q23.33 |
| Sequence: | 10; NC_000010.11 (92689955..92695647) |
Tissue Specificity
Liver and promyelocytic leukemia cell line HL- 60.
Subcellular Localizations
Nucleus.
Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Leukemia
- Obesity
- Insulin Sensitivity
- Insulin Resistance
- Neoplasms
- Cell Transformation, Neoplastic
- Malignant Neoplasms
- Impaired Glucose Tolerance
- Dysequilibrium Syndrome
- Congenital Abnormality
Interacting Proteins
- KRTAP10-5
- KRTAP10-7
- KRTAP10-8
Pathways
- Secretion
- Insulin Secretion
- Cell Differentiation
- Liver Development
- Cell Proliferation
- Gastrulation
- Localization
- Translation
- Pathogenesis
- Transport
- Pancreas Development
- Hatching
- Methylation
PTMs
- Phosphorylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HHEX
bosterbio.com/bosterbio-gene-info-cards/HHEX
References
PMID: 1360645 by Crompton M.R., et al. Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells.
PMID: 8103988 by Hromas R.A., et al. PCR cloning of an orphan homeobox gene (PRH) preferentially expressed in myeloid and liver cells.